Bioanalytical Separations and Mass Spectrometry Methods
A Thursday afternoon session entitled, “Bioanalytical Separations and Mass Spectrometry Methods,” will be held in Room W179B, beginning at 1:30 pm. The presider is Dr. Honglan Shi of the Department of Chemistry, Missouri University of Science and Technology.
A Thursday afternoon session entitled, “Bioanalytical Separations and Mass Spectrometry Methods,” will be held in Room W179B, beginning at 1:30 pmÂ, presided over by Honglan Shi of Missouri University of Science and Technology.
Kevin Clark of the Beckman Institute for Advanced Science and Technology will kick off the session with a talk on microextraction approaches for profiling neuronal RNA modifications by mass spectrometry (MS).
Next, at 1:50 pm, Michael Rerick of the University of Pittsburgh will present a paper entitled “ In Vivo Study of Ectopeptidases Using Electroosmotic Perfusion-Microdialysis Coupled with LC-MS.”
A talk on the characterization of transport of drug analogs through membrane mimics with surface plasmon resonance (SPR) spectroscopy and MALDI-MS will be presented next, by co-authors Daniel Stuart of the University of California, Riverside. This talk starts at 2:10 pm.
At 3:05 pm, co-authors Amarakoon Appuhamilage Thilini Navodi Amarakoon of the University of Arizona, will present work on “Quantification of Intracellular HNO Delivery using a Cell-permeant, Thiol-functionalized Fluorescein with CZE.” Thispresentation begins at 2:30 pm.
The next talk is entitled, “Quantifying Cell Number for Metabolomic Analysis using Calcein Blue Dye as an Internal Standard via LC-UV-MS,” and will be presented by Katherine Sandersof Saint Louis University, starting at 3:05 pm.
“Polymer Brush on Silica for RPLC-MS of Intact IgG without use of Trifluoroacetic Acid” will be presented next, by Yun Yang of Purdue University. This presentation starts at 3:25 pm.
At 3:45 pm, Lindsay of West Virginia University will present work on analytical separations to evaluate the N-glycan changes on an antibody therapeutic that guide potency. The presentation begins at 3:45 pm.
In the final talk of this session, Mohammadmehdi Azizi of the University of Texas at Arlington will present “Extraction, Fractionation and Enrichment of Membrane Proteins in Yeast Proteome by Fluoroalcohol Two-phase Systems.” The presentation begins at 4:05 pm and concludes at 4:25 pm.
Best of the Week: Food Analysis, Chemical Migration in Plastic Bottles, STEM Researcher of the Year
December 20th 2024Top articles published this week include the launch of our “From Lab to Table” content series, a Q&A interview about using liquid chromatography–high-resolution mass spectrometry (LC–HRMS) to assess chemical hazards in plastic bottles, and a piece recognizing Brett Paull for being named Tasmanian STEM Researcher of the Year.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
Determination of Pharmaceuticals by Capillary HPLC-MS/MS (Dec 2024)
December 19th 2024This application note demonstrates the use of a compact portable capillary liquid chromatograph, the Axcend Focus LC, coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis of pharmaceutical drugs in model aqueous samples.
