ASMS 2021 Afternoon Session: Challenges in MS Analysis of Complex Mixtures
This ASMS 2021 session, chaired by Yina Liu of Texas A&M University, presents a series of talks on the topics of mapping of pathogen proteins, proteomics, purification and fragmentation, metaproteomics in microbiomes, and more.
One talk of interest will be given at 3:50 by Pratik Dilip Jagtap of the University of Minnesota, on “Quantitative Metaproteomics in Microbiomes of Diverse Complexity via Data-dependent and Data-independent Acquisition Mass Spectrometry.” The authors present new developments in MS-based metaproteomics enabling improved quantitative analysis of peptides, proteins, metabolic pathways, and improved taxonomy—using data-dependent acquisition (DDA) and data-independent acquisition (DIA) approaches. This session will be in room 108 AB.
Then at 4:10 pm, Dennys Leyva of Florida International University and coworkers present “Unsupervised Structural Classification of Dissolved Organic Matter based on fragmentation pathways.” This paper highlights the use of 2D MS/MS to obtain ultrahigh resolution spectra of a SPE-DOM sample from Pantanal (Brazil). The spectra were generated by (-) ESI, followed by sequential nominal mass quadrupole isolation, collision induced dissociation (CID), and FT-ICR MS detection.
This session will be held in room 108 AB.
Best of the Week: Food Analysis, Chemical Migration in Plastic Bottles, STEM Researcher of the Year
December 20th 2024Top articles published this week include the launch of our “From Lab to Table” content series, a Q&A interview about using liquid chromatography–high-resolution mass spectrometry (LC–HRMS) to assess chemical hazards in plastic bottles, and a piece recognizing Brett Paull for being named Tasmanian STEM Researcher of the Year.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
Determination of Pharmaceuticals by Capillary HPLC-MS/MS (Dec 2024)
December 19th 2024This application note demonstrates the use of a compact portable capillary liquid chromatograph, the Axcend Focus LC, coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis of pharmaceutical drugs in model aqueous samples.
