Agilent podcast: Tip #7 Use Small Particles for more efficient separation across wide flow range

A European Union reference laboratory recently created a new method for analyzing gas chromatography (GC)-amenable pesticides in foods of animal origin.

Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.

An optimized liquid chromatography (LC) method offers improved impurity separation, no batch reproducibility issues, and is unaffected by changes in gradient delay volume settings.

Shihezi University scientists recently developed a new imprinted structure to separate acteoside (ACT) from other substances within Cistance tubulosa, or “desert ginseng.”

Here is some of the most popular content posted on LCGC International this week.