Supercritical Fluid Chromatography (SFC)

In this LCGC Blog, Kevin Schug discusses the potential machine learning has in helping predict physicochemical properties of molecules and optimizing chemical analysis processes.

Supercritical fluid extraction (SFE) was combined with supercritical fluid chromatography (SFC) hyphenated to mass spectrometry (MS) to analyze plastic additives that could be transferred into the environment from laboratory gloves.

Julien Crepier of TotalEnergies was one of the researchers that conducted this study, and he recently sat down with LCGC International to talk about his team’s findings.

Université d’Orleans and Chromisa Scientific scientists recently created a two-dimensional supercritical fluid chromatography (SFC) system with multiple heart-cutting (MHC) modes.

In this article, we review some key considerations for chromatographic technique selection and method development across the full drug process.

In this LCGC Blog, Daipayan Roy and Muhammed Qamar Farooq of Amgen discuss the history and impact of supercritical fluid chromatography (SFC) throughout the years.

Here is some of the most popular content posted on LCGC International this week.

Lausanne University Hospital scientists recently tested ultrahigh-performance supercritical fluid chromatography hyphenated to tandem mass spectrometry (UHPSFC–MS/MS) for detecting urinary endogeneous steroids.

Here are the top five articles published on LCGC International this week.

At HTC-18 in Leuven, LCGC International spoke to Claudio Brunelli about the evolution of supercritical fluid chromatography (SFC) techniques in the pharmaceutical industry.

Scientists from the Swedish university analyzed the different ways water and trifluoroacetic acid (TFA) affect peptides in sub- and supercritical fluid chromatography (SFC) separations.

The 26th Norwegian Symposium on Chromatography was held 21–23 January 2024. The symposium has strong traditions in the Norwegian separation science community, serving as a forum for excellent scientific talks, networking, and social events.

The 18th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology will take place from 28–31 May 2024 in Leuven, Belgium.

The research conducted by Jing Dong and team unveils a pioneering approach that not only unravels the complexities of Valeriana jatamansi, but also showcases the potential of advanced analytical techniques in comprehensively studying natural compounds.

To detect certain pesticides in rice, wheat, and maize, scientists recently developed a new SFC-MS/MS technique.

The Chromatographic Society will honor five scientists and academics next year, conferring its highest honor, the Martin Medal, to David McCalley and Fabrice Gritti.

A novel analytical method for the analysis of OLED materials using SFC is presented.

To better understand the purity of therapeutic peptides, scientists from Germany, studied the effects supercritical fluid chromatography (SFC) could have during the analysis.

Scientists used supercritical fluid chromatography (SFC) and ultrahigh-pressure liquid chromatography (UHPLC)—both coupled with high-resolution mass spectrometry (HRMS)—to analyze various types of chlorinated paraffins (CPs) in fish oil-based dietary supplements.

Small modifications to the way measurements are approached can enable reductions in the waste generated and carbon dioxide produced during an analysis.

The 27th International Symposium on Separation Sciences (ISSS 2023) will be held 24–27 September 2023 in Cluj-Napoca, Romania. Here’s a sneak preview of what attendees can look forwards to.

This instalment of “Column Watch” presents many of the highlighted topics and trends observed at this exceptionally well-run symposium.

A new study proposes a new subtraction model to characterize non-polar stationary phases.

At HPLC 2023, LCGC spoke with John Langley of the University of Southampton in the UK. These clips comprise one of several HPLC interviews that were conducted at the conference.

In his plenary lecture at HPLC 2023, Michal Holčapek presented his team's findings on how chromatography can help scientists record the human lipodome and better our understanding of diseases.

Why is SFC becoming increasingly more important as a sustainable analytical technique?

Exploring the impact of green chemistry on analytical chemistry and GC is the focus of this instalment of "GC Connections".

The Chromatographic Society and the Separations Science Group of the Analytical Division of the Royal Society of Chemistry are pleased to announce Emerging Separations Technologies 2023 is to be held 24–25 May 2023, at RSC Burlington House, London, UK.

Everyone is talking about sustainability, and organizations are creating sustainability programs. But what does green chemistry really mean, and how does it apply to gas chromatography?

This study highlights the benefits of using ternary eluent compositions in SFC for separating peptides.