Indirect Suppressed-Conductivity Ion Chromatography
The authors demonstrate a new detection method, indirect suppressed conductivity, for various anions of weak acids separated by ion chromatography. They analyzed three groups of anions, including amino acids such as leucine, taurine, phenylpropionic acid, and phenol; malic and tartaric acids; and lactic, formic, and benzoic acids. The authors describe the mobile phases, detection limits, and correlation coefficient of rectilinear relationships for each anion type.
LCGC 18(2), 200–204 (2000).
Overcoming Common Challenges to Determine Residual Impurities Using IC in APIs with Limited Water
December 10th 2024Organic solvents are generally not compatible with ion chromatography (IC) systems. The approach presented here assists the use of organic solvents for sample preparation and provides a mechanism for the removal of the organic solvents from the chromatographic flow path.
