April 1st 2025
Interest in applying artificial intelligence (AI) and machine learning (ML) to chromatography is greater than ever. In this article, we discuss data-related barriers to accomplishing this goal and how rethinking chromatography data systems can overcome them.
Ingenious Ways to Manipulate Peak Integration?
February 1st 2024Tired of life as your analytical results are always out of specification (OOS)? Fed up with yet another laboratory investigation? Get those rotten chromatograms to generate passing results by learning ways to manipulate peak integration from the experts... and now I have your undivided attention...and how reviewers, QA and inspectors can detect them!
The LCGC Blog: Are You Sick of Hearing About ChatGPT?
August 15th 2023Are you interested by ChatGPT's vast potential? Or are you getting tired of reading or hearing about ChatGPT? If the latter, this blog post might give you some tips and tricks on taking advantage of ChatGPT while avoiding its application beyond its intended scope.
An Interview with AI About Its Potential Role in Separation Science
May 17th 2023We interviewed an AI program (ChatGPT) for LCGC North America asking questions about AI and its role in various applications for separation science to include data analysis, and high performance liquid chromatography (HPLC), hydrophilic-interaction chromatography (HILIC), reversed-phase liquid chromatography (RPLC), liquid chromatography–mass spectrometry (LC–MS), gas chromatography–mass spectrometry (GC–MS), high resolution mass spectrometry (HRIM–MS), high resolution tandem mass spectrometry (HRMS/MS), and related topics.
What’s Good About the WHO Good Chromatography Practices Guidance? Part 2
February 1st 2021In September, the World Health Organization (WHO) issued a new guidance document on Good Chromatography Practices. What guidance does it contain and is it useful? Has the document failed its system suitability test (SST) acceptance criteria?
What’s Good About the WHO Good Chromatography Practices Guidance? Part 1
November 1st 2020In September the World Health Organisation (WHO) issued a new guidance document on Good Chromatography Practices. What guidance does it contain and is it useful? Has the document failed its SST acceptance criteria?
The LCGC Blog: Does the Paper in the Column Box Mean Anything Anymore?
September 30th 2020Pretty much every commercial chromatography column has some sort of release testing done on it before it leaves the manufacturer. Just how valuable are those tests to the end user? Should column Certificates of Analysis go straight to the rubbish bin?