Biopharmaceuticals and Protein Analysis

Scientists from Naif Arab University recently used a new approach to protect amide-based synthetic cannabinoids from degradation and esterification during GC–MS analysis.

Here are the top five articles that the editors of LCGC International published this week.

Scientists from the University of Geneva in Geneva, Switzerland and AstraZeneca in Mölndal analyzed how HILIC is related to the connections between oligonucleotide structures and diastereomer separation.

University of Tübingen scientists recently tested a new approach to hydrophilic-interaction chromatography (HILIC) to address retention time repeatability issues.

Scientists from Roche Diagnostics in Germany are testing a new liquid chromatography (LC)-based approach for advancing process analytical technology (PAT) in biopharmaceutical processing.

The editors of BioPharm International spoke with Christine Rozanas, PhD, global product marketing manager at Cytiva, to discuss the advantages and persistent challenges with implementing continuous downstream chromatography.

Scientists from the University of Isfahan in Iran recently developed a new system for detecting and quantifying B vitamins in human samples.

Scientists from Hebei Medical University developed a sensitive liquid chromatography-tandem mass spectrometry (LC–MS/MS) method for analyzing free fatty acids in human serum.

Scientists from the University of Edinburgh evaluated different polishing chromatography elution strategies to optimize output.

LCGC International sat down with Kemi Osho of the University of Nevada, Reno (UNR) to discuss her career and work with the Females in Mass Spectrometry (FeMS) group.

A session at the HTC-18 conference in Belgium featured speakers from around the world detailing the latest advances in biopharmaceutical analysis.

Here are the top five articles that the editors of LCGC International published this week.

During the 18th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology, experts presented a workshop on different ways multidimensional liquid chromatography can be applied.

In preparation for ASMS 2024, we sat down with Elizabeth Neumann of the University of California, Davis about her upcoming workshop.

A recent paper discusses advances in hydrophilic interaction chromatography (HILIC) in the analysis of therapeutic oligonucleotides and their impurities.

Scientists from Changchun University of Chinese Medicine used UHPLC-Q-Orbitrap-MS/MS analysis to identify the active compounds in TongFu XieXia Decoction for treating intestinal obstruction.

Scientists from the Lunan Pharmaceutical Group explored the use of UHPLC-MS/MS to test the effects of Shouhui Tongbian capsules (SHTBs) on slow transit constipation (STC).

Scientists from Manipal Academy of Higher Education in India recently discussed different protein profile pattern analysis techniques and how they can help allow for universal screening.

Scientists from Vanderbilt University recently tested a new means of imaging mass spectrometry (IMS) for isotopically resolved intact proteins.

Scientists from Chongqing University Cancer Hospital recently developed a new system for analyzing the potential impact of retention time (RT) prediction on targeted LC–MS-based lipidomics.

Scientists from the Chinese Academy of Sciences recently tested out a new type of micro gas chromatographic column (µGCC) for separating light hydrocarbons.

Scientists from Florida State University used Marfey’s reagent and reversed-phase liquid chromatography–tandem mass spectrometry (LC–MS/MS) to analyze D-amino acids.

Michelle Colgrave of Edith Cowan University and Australia’s national science agency is the recipient of the 2024 Harvey W. Wiley Award.

Swedish and German scientists recently made a new system for detecting of selective androgen receptor modulators (SARMs) in human samples.

Scientists from the University of Córdoba in Córdoba, Spain recently used liquid chromatography–tandem mass spectrometry (LC–MS/MS) to comprehensively profile human ceramides to determine their reactions to diseases.

Here are the top five articles that the editors of LCGC International published this week.

In this edition of the LCGC Blog, Jonathan Edelman discusses the 43rd Annual International Symposium and Exhibit on the Separation, Purification, and Characterization of Biologically Important Molecules (ISPPP) and provides a timeline for the upcoming conference.

The 26th Norwegian Symposium on Chromatography was held 21–23 January 2024. The symposium has strong traditions in the Norwegian separation science community, serving as a forum for excellent scientific talks, networking, and social events.

Scientists from Auburn University recently investigated how natural deep eutectic solvents (NADES) can be incorporated into high-performance liquid chromatography (HPLC) mobile phases.

Scientists recently tested a new system for detecting and extracting favipiravir from plasma samples.