GPC-LC-MS-MS Method for Mycotoxins in Edible Oil
March 4th 2009Researchers at the Munich Technical University and Bavarian Health and Food Safety Authority have developed a comprehensive mycotoxin screening method based on the use of an LCTech GPC ULTRA gel permeation chromatography (GPC) instrument, which is distributed in North America by Pickering Laboratories (Mountain View, California) for sample cleanup before separation and detection.
Ionic Liquid-Based Single-Drop Microextraction of Chlorobenzenes
March 4th 2009A research group from the University of Valencia (Valencia, Spain) and the University of Alicante (Alicante, Spain) used ionic liquid?based single-drop microextraction followed by gas chromatography (GC) to analyze chlorobenzenes in real water samples.
Ask the Editor: Replacing Acetonitrile
March 2nd 2009The answer to the following question was provided by LCGC's "LC Troubleshooting" columnist John Dolan. Q: Since acetonitrile is in short supply and the prices have sky-rocketed in recent months, what can be done about replacing this solvent with others for various chromatography applications?
Determination of Aminoglycoside Antibiotics by HPLC with ELSD
March 2nd 2009Streptomycin and neomycin are members of the family of antibiotics called aminoglycosides. Aminoglycoside antibiotics are complex organic molecules produced by streptomyces strains and are extremely important in clinical medicine, due to their efficacy and low cost.
Practical Aspects of Solvent Extraction
March 1st 2009Columnist Ron Majors discusses some of the practical considerations in the successful application of the popular yet age-old technique of solvent extraction (also known as liquid–liquid extraction, or LLE). After a brief review of the basics, guidelines on the selection of the appropriate extraction solvents and how to use acid–base equilibria to ensure efficient extractions of ionic and ionizable compounds are provided. Problems in LLE and the solutions to these problems are highlighted. A newer technique called dispersive liquid–liquid microextraction (DLLME) is introduced.