Dispersive Liquid-Liquid Microextraction in Antiseptic Agent Analysis
Researchers from the Chinese Academy of Sciences (Beijing, China), Beijing Technology and Business University (Beijing, China), and Hebei University (Shijiazhuang, China) used dispersive liquid?liquid microextraction and ultrahigh-pressure liquid chromatography to analyze triclosan, triclocarban, and methyl-triclosan in aqueous samples.
Researchers from the Chinese Academy of Sciences (Beijing, China), Beijing Technology and Business University (Beijing, China), and Hebei University (Shijiazhuang, China) used dispersive liquid–liquid microextraction and ultrahigh-pressure liquid chromatography to analyze triclosan, triclocarban, and methyl-triclosan in aqueous samples. Triclosan and triclocarban are antibacterial and antifungal agents found in some antiseptic soaps, nad methyl-triclosan is an environmental transformation product of triclosan. They examined factors such as extraction solvent and dispersive solvent type and volume, extraction time, and pH. They found that the method was suitable for the rapid determination of the compounds in real water samples.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.
