All News

There has been a significant resurgence in the development of antibody-drug conjugates (ADC) as target-specific therapeutic agents for cancer treatments. This article presents a method for DAR determination based on size-exclusion chromatography with multi-angle light scattering (SEC?MALS) combined with ultraviolet (UV) absorption and differential refractive index (dRI) detection.

Would the truly quantitative detector please stand up!

The China Chromatography Network (www.Sepu.net) was established in 1999. Since its inception, it has always upheld its mission to provide a chromatography portal with information of the highest quality.

Previously unreported biological activity of endocrine disrupting chemicals (EDCs) has been detected in water samples from 14 states in the US by researchers at the National Cancer Institute, Maryland, USA.1

"Lean" approaches are used to reduce wastes and costs when performing chromatographic procedures. The terminology of this approach is introduced in this article, together with illustrative examples and suggestions.

Higher levels of aromatic amino acids may indicate early stage gastric cancer, according to a research group in China.1

The National Aeronautics and Space Administration (NASA) has awarded Xylem Inc., (White Plains, New York) a $300,000 contract to provide special mass spectrometry technology with a goal of detecting water on the moon.

Agilent Technologies (Santa Clara, California, USA) has selected Dr Robert Gerszten to receive the Agilent Thought Leader Award.

LGC (Cambridge, UK) has acquired the Bioanalytical Sciences division of Quotient (Cambridge, UK).

Click here to view the complete LCGC Europe E-Newsletter from 11 January 2013

Click here to view the complete E-Separation Solutions newsletter from January 10, 2013.

Thermo NA - Analysis of 2-aminobenzamide Labeled Dextran Ladder on a Solid Core HPLC Column

Thermo NA - Analysis of Estrogens Using a Solid Core HPLC Column

Thermo NA - Rapid Separation of Analgesic Compounds Using a Solid Core HPLC Column

Thermo NA - Analysis of 2-aminobenzamide Labeled Dextran Ladder on a Solid Core nanoLC Column

Thermo NA - Analysis of 3 Nonsteroidal Anti-inflammatory Drugs Using a Solid Core HPLC Column

Thermo NA - Separation of a Mixture of Vitamin K Isomers Using a Solid Core HPLC Column at Sub-ambient Temperature

Restricted-access media (RAM) offer many advantages and can make it easier to achieve efficient and reproducible on-line sample preparation. In spite of this, these media have been underutilized. It is time for more research into RAM.

Thermo Fisher Scientific (Massachusetts, USA) has acquired picoSpin (Colorado, USA), the company credited with the creation of the world?s first miniature nuclear magnetic resonance (NMR) spectrometer. picoSpin first introduced the award-winning shoebox-sized NMR spectrometer in 2010.

Higher levels of aromatic amino acids may indicate early stage gastric cancer, according to a research group in China.1

Click here to view the complete E-Separation Solutions newsletter from January 3, 2013.

An explanation of each stage in a typical SPE protocol

Pittcon 2013 Award Winners Announced

A preview of what Pittcon will offer chromatographers in Philadelphia this year.

The 29th International Symposium on MicroScale Bioseparations (MSB 2013) will be held 10–14 March 2013, at the University of Virginia in Charlottesville, Virginia, USA. The conference will build on the rich history of separation science and discuss a wide spectrum of current microscale bioseparation techniques.

An excerpt from LCGC's e-learning tutorial on solid-phase extraction at CHROMacademy.com

Likely sources of error are filtration and vial materials.

Many edible oils contain natural antioxidants that protect the oil from lipid oxidation, Knowledge on the identity of these oxidation inhibitors is crucial to find natural ways to protect healthy, unsaturated fats and oils from turning rancid. This article describes a new assay that allows rapid quantification of the lipid oxidation inhibting potenital of pure compounds or liquid chromatography (LC) fractions.

More questions about gases and their delivery to a GC instrument

The use of a gradient scouting run can be a powerful tool to jump-start method developent. But what conditions should be chosen, and what do we do with the results?