Impact of New Columns on Drug Development
November 2nd 2014An examination of the development of new types of columns based on different particle types, sizes, and other physical characteristics and how they can improve the speed and efficiency of HPLC used to support more expansive and complicated analyses.
Electronic Control of Carrier Gas Pressure, Flow, and Velocity
November 1st 2014Have you wondered how your GC system sets and controls gas pressures, flows, and carrier gas velocities electronically? Here, we describe the requirements for and the operation of electronic gas control systems for GC columns and detectors.
Winners of the 2015 LCGC Chromatography Awards To Be Honored in Pittcon Symposium
October 28th 2014LCGC, the leading resource for separation scientists, is proud to announce that Joseph Jack Kirkland and Caroline West are the winners of the eighth annual LCGC Lifetime Achievement and Emerging Leader in Chromatography Awards, respectively.
SPE and Analysis Of Organochlorine Pesticides and Inline Cleanup from Water
October 28th 2014In water samples, OCPs are monitored by the U.S. Environmental Protection Agency by various methods including methods EPA 508, EPA 608, and EPA 8081. The use of solid phase extraction (SPE) can rapidly increase both extraction efficiency and reduce lab solvent usage. By implementing the FMS TurboTrace® ABN system with its dual cartridge functionality, an in-line Florisil cartridge can be added to perform automated extract clean-up during the elution step.
Characterizing Antibody-Drug Conjugates for Biotherapeutics with the Light Scattering Toolkit
October 24th 2014This article is an overview of the different types of antibody-drug conjugates (ADC) characterization that can be performed with the light scattering toolkit to support the development of biotherapeutics.
Foodomics Approach Detects Anticancer Polyphenols in Rosemary
October 24th 2014A study published in the journal Analytical Chemistry presents the application of a foodomics approach – combining transciptomics with metabolomics – to determine the anticancer mechanism of action of polyphenols contained in Rosmarinus officinalis L., commonly known as rosemary.1
Sample Amount Normalization in Metabolomics
October 24th 2014A simple dansylation metabolite assay (DMA) for sample normalization that is similar to the bicinchoninic acid (BCA) protein assay widely used in proteomics has been presented in the journal Analytical Chemistry. The DMA assay is performed following sample extraction to determine the total metabolite concentration, which can then be used to determine the volume of sample needed to ensure that all samples contain the same concentration of metabolites.