Application Notes

Direct injection LC–MS/MS method, optimized with dual ionization sources for the determination of 214 regulated contaminants using a PerkinElmer QSight ® 420

In this application note, a method for the identification of VOCs in plant material utilizing a headspace technique is presented.

Liquid-liquid extraction and large-volume direct injection of extract into Clarus® SQ8 GC/MS with D-Swafer™ system for concentration, separation, quantification of SVOCs

This work demonstrates an ion exchange method for the characterization of Cr6+ in potable drinking water using our NexSAR HPLC-ICP-MS Speciation Solution.

Using Empower CDS and NuGenesis LMS to develop an archive strategy that reduces backup and recovery times and removes manual intervention is demonstrated.

Companies can seek outside help for backup and restore, disaster recovery, and system administration, but responsibility for regulated data remains with the company.

VITAQUEST, a contract manufacturer of dietary supplements, used NuGenesis LMS to automate its workflows, improve lab efficiency, and reduce the risk for data errors.

This study shows how coupling Waters’ Empower CDS with cloud technology allowed a pharmaceutical company to streamline its global operations and connect each of its labs.

As workers return to the analytical laboratory, it is critical that they are provided with a safe working environment, but 35% of Coronavirus sufferers are asymptomatic.

This white paper explains the 21 CFR Part 11 and EU EudraLex Annex 11 compliance readiness of Waters Empower Software for the regulated scientific laboratory.

This case study demonstrates the advantages of pairing Empower CDS with NuGenesis LMS to improve the availability of your CDS data and maximize its effectiveness.

This application describes the isolation of cannabinoids from a hemp oil extract. Analytical- and preparative-scale HPLC with MS detection is used for separation.

This application describes the isolation of cannabinoids from a hemp oil extract. Analytical- and preparative-scale HPLC with MS detection is used for separation.

A&M Stabtest, an independent CRO in the pharmaceutical industry, reduced time-consuming and error-prone manual steps in the chromatographic testing process.

An investment in Waters NuGenesis LMS helped a global pharmaceutical CDMO meet demands for data integrity regulatory compliance and laboratory management needs.

This study demonstrates Waters ACQUITY UPLC with PDA/QDa technology and Empower Software were integral to successful method lifecycle management at Hovione, a global CDMO.

Companies can reduce the fallout of a disaster via a business continuity plan with appropriate hardware and software, including Waters Empower BC LAC/E with SecureSync.

Accurate detection of HAA’s is paramount for the prevention of over oxidation, while still managing enough water sanitation to eliminate water borne pathogens.

Combining the benefits of the ACQUITY APC System with the ACQUITY UPLC Refractive Index (RI) Detector and the ACQUITY QDa Mass Detector yields laboratory efficiencies.

The selection of appropriate column chemistries to separate eighteen polymer additives are routinely monitored in extractables and leachables (E&L) workflows.

A flexible analytical system was used in conjunction with a well-defined informatics workflow to elucidate degradation markers in Li-Ion battery electrolytes.

Combining the APC System with WinGPC UniChrom™ software allows researchers to increase the peak capacity of their research.

This application note demonstrates Evolved Gas Analysis (EGA) and Multi-step Pyrolysis (MSP) with GC/MS on two different tea bag samples.

Collaborative efforts at Virginia Tech University drive better materials through polymer innovation and additive manufacturing.

YMC’s latest HIC column is used to analyse the DAR of Brentuximab Vedotin allowing higher flow rates and shorter run times thanks to the pressure resistant particle.

YMC’s HIC columns, BioPro HIC HT, and BioPro HIC BF address separation requirements of different compounds. The separation behaviour of two mAbs is demonstrated.

This application note shows how a mixture of seven in-house mAbs, as well as the molecular variants of two mAbs, were characterised via HIC-MS using YMC’s BioPro HIC BF column.

In this application note the DAR of the SigmaMAb ADC-mimic was determined using YMC’s BioPro HIC BF column and a nanospray ionisation mass spectrometer.

Monoclonal antibodies and their oxidised species are separated using YMC’s more hydrophobic BioPro HIC BF column, dedicated for low hydrophobicity proteins and oxidised mAb variants.

Four therapeutic mAbs of different species, isotypes, and pI together with their variants were analysed using pH and salt gradient mode using YMC’s non-porous BioPro IEX SF.