Application Notes

FFF can provides solutions for biopharmaceutical, nanomedicine, environmental, industrial and natural macromolecule, agriculture, and cosmetic sectors.

Elution profiles based on mAb glycan structures produced by the TSKgel® FcR-IIIA-NPR™ affinity chromatography column correlate with results from HILIC glycan profiling.  

In this study the goal was to characterize the MCF-7 tumour exosome by size using AF4 coupled to MALS, and by mass using centrifugal field-flow fractionation (CF3).

ÄKTA systems are used for the purification, separation, and characterization of proteins and antibodies in the pharmaceutical area and in biomolecular research.

In the field of biomedical therapy, imaging, and chemotherapy drug-loaded liposomes have shown great potential for treating diseases. FFF can measure the amount of drug ‘cargo’ loaded into these drug delivery particles, which is one of the main analytical challenges in nanomedicine.

In this application note, we describe the application of asymmetrical flow field-flow fractionation (AF4) coupled to a multi angle light scattering (MALS) detector and a UV/Vis diode

Highlighting the use of the dial-a-mix method for screening different mobile-phase pH conditions during method development of IEX charge variant analysis.

This application note details the development of a HPLC method for analyzing CBD and Melatonin in an over-the-counter sleep aid.

This application note highlights the ability of YMC-Triart C18 to separate 11 common cannabinoids encountered during potency testing.

A loading study for purifying cannabidiol (CBD) from a commercially available “high-CBD” hemp oil extract

This application note demonstrates the quantitative analysis of microplastics using direct thermal desorption (TD) combined GC–MS.

Demonstrating the use of YMC’s new 2µm Diol stationary phase for scaling down size exclusion analyses

The low sensory threshold of 2,4,6-tricholoranisole (TCA), a major contributor of wine cork taint, is hard to detect without a sensitive instrument like the Pegasus® BT.

Here we present an innovative approach for the characterization of nanoplastic particles using centrifugal field-flow fractionation coupled with UV, multi angle light Scattering detection, and raman microscopy.

This application note provides an optimised and validated fully automated sample preparation and LC–MS/MS analysis solution for seven target nitrosamines in two classes of drug substance.

A quick, easy, effective procedure to identify and quantitate Kratom analytes in blood and urine using Clean Screen® XCEL I SPE cartridges and a Selectra® C18 UHPLC column.

Being the recognized method in worldwide regulations, Magnetic Sector offers advantages when it comes to routine quantitative analysis of Dioxins and other POPs.

UCT’s polymeric Styre Screen® HLD sorbent analyzes a wide range of neutral drugs in oral fluid.

This application note describes a simple and robust solid-phase extraction (SPE) procedure for amphetamines in blood, plasma, serum, urine, and tissue samples.

This application note outlines a solid-phase extraction (SPE) and LC-MS/MS method for the analysis of 19 synthetic cannabinoids in urine

This application note describes a simple and robust solid-phase extraction (SPE) procedure for Chloroquine, Hydroxychloroquine, and Desethylchloroquine in urine.

This application note outlines a simple 3 step method for the extraction of Loperamide and its main metabolite, N-desmethyl Loperamide, from blood using UCT’s Clean Screen® XCEL I SPE columns.