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Method Development of IEX mAb Separations Using YMC BioPro IEX Columns and Dial-a-Mix
Highlighting the use of the dial-a-mix method for screening different mobile-phase pH conditions during method development of IEX charge variant analysis.
HPLC Separation of Cannabidiol and Melatonin on YMC-Triart C18
This application note details the development of a HPLC method for analyzing CBD and Melatonin in an over-the-counter sleep aid.
Increasing Throughput for Forensic Screening of Raw Case Samples Using the Agilent QuickProbe GC/MS System
Separation of 11 Cannabinoids on YMC-Triart C18
This application note highlights the ability of YMC-Triart C18 to separate 11 common cannabinoids encountered during potency testing.
Black Pepper Authenticity Workflow Using the High-Resolution Agilent 7250 GC/Q-TOF v2
Preparative Purification of Cannabidiol from Hemp Oil Extract
A loading study for purifying cannabidiol (CBD) from a commercially available “high-CBD” hemp oil extract
Addressing the Challenges of Microplastic Characterisation
This application note demonstrates the quantitative analysis of microplastics using direct thermal desorption (TD) combined GC–MS.
Tips for Regulated Laboratories, Part 2
Workflow for Food Classification and Authenticity using Yerba Mate and High-Resolution GC/Q-TOF
Automated MRM Method Development for Pesticides in Cannabis Using the Agilent MassHunter Optimizer for GC/TQ
Investigation of Pore Size, Particle Size, and Column Geometry Effects on SEC Analysis of Monoclonal Antibodies
Demonstrating the use of YMC’s new 2µm Diol stationary phase for scaling down size exclusion analyses
Detecting Cork Taint with Pegasus® BT
The low sensory threshold of 2,4,6-tricholoranisole (TCA), a major contributor of wine cork taint, is hard to detect without a sensitive instrument like the Pegasus® BT.
Separation, chemical identification, and size characterization of nanoplastic particles using Raman microscopy and FFF-MALS
Here we present an innovative approach for the characterization of nanoplastic particles using centrifugal field-flow fractionation coupled with UV, multi angle light Scattering detection, and raman microscopy.
Fully Automated Solution for Nitrosamines Analysis
This application note provides an optimised and validated fully automated sample preparation and LC–MS/MS analysis solution for seven target nitrosamines in two classes of drug substance.
Extraction of Mitragynine and 7-Hydroxymitragynine from Blood and Urine
A quick, easy, effective procedure to identify and quantitate Kratom analytes in blood and urine using Clean Screen® XCEL I SPE cartridges and a Selectra® C18 UHPLC column.
What Are the Advantages of Using Magnetic Sector GC–HRMS technology for Dioxin and POPs Analysis?
Being the recognized method in worldwide regulations, Magnetic Sector offers advantages when it comes to routine quantitative analysis of Dioxins and other POPs.
Barbiturates, Benzodiazepines, and THC in Oral Fluid
UCT’s polymeric Styre Screen® HLD sorbent analyzes a wide range of neutral drugs in oral fluid.
Extraction of Amphetamines from Biologicals
This application note describes a simple and robust solid-phase extraction (SPE) procedure for amphetamines in blood, plasma, serum, urine, and tissue samples.
Analysis of Synthetic Cannabinoids in Urine
This application note outlines a solid-phase extraction (SPE) and LC-MS/MS method for the analysis of 19 synthetic cannabinoids in urine
Chloroquine, Hydroxychloroquine, and Desethylchloroquine in Urine
This application note describes a simple and robust solid-phase extraction (SPE) procedure for Chloroquine, Hydroxychloroquine, and Desethylchloroquine in urine.
Extraction of Loperamide and N-Desmethyl Loperamide from Blood
This application note outlines a simple 3 step method for the extraction of Loperamide and its main metabolite, N-desmethyl Loperamide, from blood using UCT’s Clean Screen® XCEL I SPE columns.
Characterization of Organochlorine Pesticides in Black Tea
The Torion® T-9 GC/MS system has characterized several high boiling point organochlorine pesticides in tea samples in less than 10 minutes.
Analyzing Azithromycin Using a Quasar™ C18 Column
This application note discusses using a Quasar™ C18 column to analyze azithromycin, an antibiotic used to treat various bacterial infections.
Analysis of Veterinary Drugs in Chicken by SPME-UHPLC/MS/MS
SPME-UHPLC/MS/MS offers an efficient alternative for the analysis of veterinary drug residues in animal tissue as compared to traditional sampling procedures.
HPLC Analysis of the Synthetic Antibiotic Ciprofloxacin
The Quasar biphenyl HPLC phase offers high efficiency separation and excellent peak shape of the synthetic antibiotic, ciprofloxacin.
Analyzing Cephalosporins Using a Quasar Biphenyl LC Column
This application note describes using a Quasar biphenyl LC column in analyzing several cephalosporins, a mixture of first and second generation β-lactam antibiotics.
Characterization of Nano-Pharmaceuticals with FFF-MALS-DLS
FFF-MALS-DLS provides the detailed characterization of nano-pharmaceuticals that is essential for development and regulatory filing.
Boosting LC Method Efficiency with Allowable Compendial Adjustments
Method Validation for Atrazine Analysis
A highly sensitive, validated method for atrazine determination in different water types using the QSight 420 LC–MS/MS employed a simple filtration and direct injection.
Analysis of Challenging Polar Contaminants in Water
Using the LX50 UHPLC and QSight 420 triple quad MS, three analytical methods were developed to provide sensitive, reproducible results without the need for pre-concentration steps.