Application Notes

This application note summarizes a validated procedure developed by the US Food and Drug Administration (FDA) for the measurement of 16 PFASs in food using a QuEChERS sample preparation approach.

This application looks at the differences in chromatography between the Quasar C18 and AQ phase chemistries for the analysis prednisolone, prednisone, and cortisone.

This technique achieves highly reproducible and fast analysis of organochlorine pesticides in water by coupling automation with the use of a disperser solvent.

The Eclipse Neutrino, a premier monomer analyzer process gas chromatograph, couples MSD, PDHID, and FID detectors to characterize an extremely broad range of analytes from fixed gases to C5+. Quickly detecting ppm-ppb levels of impurities and catalyst poisons.

Robust and accurate primary sequence confirmation and monitoring of post-translational modifications of the SARS-CoV-2 spike protein using the BioAccord LC–MS system.

Eliminate the need for column conditioning, improve recovery, and improve repeatability by minimizing non-specific oligonucleotide interactions with metal surfaces.

A rapid, sensitive, and reproducible method for understanding the SARS-CoV-2 spike protein N-glycosylation profile using the GlycoWorks RapiFluor MS N-Glycan Kit.

Review of the best practices for oligonucleotide analysis and purification to achieve high quality oligonucleotides for COVID-19 diagnostic or therapeutic applications.

A HILIC method for baseline separation of ribavirin from isobaric and structurally similar species within 6 minutes using an ACQUITY UPLC BEH Amide column.

This work demonstrates how to achieve sharper peaks and faster elution of basic analytes like umifenovir using a mixed-mode Atlantis PREMIER BEH C18 AX column.

We discuss the role of LC and LC–MS for select COVID-19 applications to better understand the use of analytical technologies mobilized in the fight against the pandemic.

The evaluation of different salt gradients was performed on the Agilent 1290 Infinity II Bio LC System and analyzed for resolution as well as reproducibility.

This application note demonstrates the DAR determination of brentuximab vedotin using HIC. Excellent reproducibility was found with the Agilent 1290 Infinity II Bio LC.

Method transfer can be easy and convenient with the Agilent 1290 Infinity II Bio LC. Excellent method compatibility is demonstrated using the peptide-mapping workflow.

In this application note, we present the Agilent 1290 Infinity II Bio LC as the system of choice for peptide mapping with excellent precision for shallow gradients.

This application demonstrates the superior resolution in size-exclusion chromatography (SEC) of proteins made possible by the Agilent 1290 Infinity II Bio LC System.

This white paper demonstrates a vendor’s perspective on recent trends in regulations and the potential future direction for the industry.

This application note demonstrates the direct analysis of biogenic amines in Tempranillo red wine using ion pair chromatography prior to MS analysis.

This application note demonstrates the direct analysis of biogenic amines in Tempranillo red wine using ion pair chromatography prior to MS analysis.

This application note uses ChromCompare+ chemometrics platform for GC–MS to identify significant differences across essential oil batches for quality control & authenticity studies.

Known carcinogen, acrylamide is formed during food production processes such as roasting. This study details the use of SIFT–MS to monitor for this VOC in real time.

This white paper demonstrates a vendor’s perspective on recent trends in regulations and the potential future direction for the industry.

Comprehensive two-dimensional gas chromatography (GC×GC) analysis results in superior resolving power and remarkable peak capacity. The heart of a GC×GC system is the modulator. This interface continuously collects the first column eluate into small fractions and re-injects them individually onto the second dimension.

Analysis of flame retardant Tris(1,3-dichloro-2-propyl)phosphate (TDCPP) in polyurethane foam by Evolved Gas Analysis (EGA) and Multi-step Pyrolysis (MSP) GC–MS.

Revolutionize your bioanalytical sample preparation. Search application notes by your compounds of interest, application area, SOLA chemistry phases, or SOLA formats.

The baseline separation of various chlorophenols, that only differ in the amount and/or position of the chlorine substituents, is made possible using YMC-Triart C18 ExRS.

Dioxins and other persistent organic pollutants are everywhere. Labs analyze samples to quantify and guarantee their results are compliant with regulations and controls.

Modified nucleosides, either natural or synthetic, often provide RNA with distinctive properties useful in diagnostics or therapeutics.  

Characterization of technical polymers by light scattering and field-flow fractionation (FFF-MALS) is reviewed and contrasted with the more common technique, SEC-MALS.