Application Notes

This application note investigates the differences between packaging of normal and inferior hand-sanitizing wipes using EGA and multi-step pyrolysis GC–MS.

The 30 mg Microlute® CP Strong Cation Exchange (SCX) 96 well plate compares performance in recoveries and reproducibility against five competitor loose-filled 30 mg SCX products.

This note demonstrates the determination of PAH4 inedible oils with automated sample enrichment and matrix elimination (online solid-phase extraction - online SPE).

This application note presents the rapid analysis and quantification of carbohydrates in various matrices, such as syrups, honeys, and molasses, at low running costs.

This application demonstrates the efficiency, throughput, and reliability of a dual-injection system for finished pharmaceutical products and in-process APIs.

What has happened over the last two years since the global helium shortage was the hot topic in GC, where do we currently stand, and what is the short-term outlook?

Cannabinoids have similar molecular structures, making purification a challenging step. Learn how centrifugal partition chromatography can simplify this process.

Technical note describing the use of tandem ionisation for BenchTOF2 mass spectrometers, to acquire both hard and soft electron ionisation in a single analysis

Using TD–GC×GC–TOF-MS for profiling of biomarkers in breath and data mining tools to uncover hidden compositional changes using automated untargeted workflows

TI data improves discovery workflows by reducing the frequency of false positives; finding significant class-based differences between GC & GC×GC chromatograms

The use of headspace sorptive extraction with GC×GC–TOF-MS to compare the volatile profiles of ground meat and plant-based substitutes

Learn how your lab can benefit from smarter GC‒MS instruments and workflows to discover more from your samples and deliver improved business outcomes

Using GC×GC–TOF-MS and tandem ionisation to identify trace additives in gasoline to automatically uncover differences between gasoline blends

Showing how the comprehensive data acquired using GC×GC–TOF-MS with tandem ionisation can uncover the subtle differences between brand and imitation fragrances

This application note shares new chiral separations for the anti-viral, COVID-19 treatment Remdesivir and its phosphoramidite and nucleoside key-starting materials.

This application demonstrates a reliable GC–MS/MS method for analysis of nitrosamine drug products including the three impurities NDMA, NDEA, and NDBA listed by US FDA.

Automated extraction of methylmalonic acid from serum facilitates accurate and robust analyte quantification.

This application evaluates routine liquid handling sample prep methods using Andrew+ Pipetting Robot for mixing, serial dilutions, and standard prep in food analysis.

This work highlights automated calibration curve generation using Andrew+ Pipetting Robot for accurate and reproducible LC–MS quantification of nitrosamine impurities.

This work encapsulates the reliability that this new, seamless technology, Otto SPEcialist Positive Pressure Manifold, provides during a method of solid-phase extraction.

This application note highlights the automated sample preparation and extraction of itaconic acid from human plasma with subsequent LC–MS/MS analysis and quantification.