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In-well Hydrolysis and Clean-up of 39 Pain Management Drugs Using Strata-X-Drug B Plus SPE and Analysis with a Kinetex Biphenyl Column
An in-well hydrolysis solid-phase extraction (SPE) product is used for an easy clean-up solution for the urine sample matrix to save time and transfer steps.
Isolation of Low-Level Testosterone from Plasma by LC–MS/MS Analysis in Conjunction with Novum PRO SLE v2
Testosterone was isolated from plasma using Novum PRO 96-well plates SLE sample preparation.
Steroid Panel Extraction from Plasma Using Novum PRO Simplified Liquid Extraction (SLE)
An SLE media provides a fast sample prep method. Adding advanced manufacturing processes leads to high recoveries and low variation between samples.
Fast Clean-up of Whole Blood Using Phree Phospholipid Removal and Analysis of 39 Pain Management Drugs by Kinetex 2.6 µm Biphenyl
In this application, serum was cleaned up and compared with both a single protein precipitation protocol and also by the addition of a phospholipid removal product.
Untargeted Screening of PFAS
Detailing how thermal desorption GC–MS can be used to monitor the release of PFAS during the application of aqueous film-forming foam
PFAS Analysis Using EPA Method 537.1
This brief demonstrates the extraction and analysis of PFAS compounds in water following EPA method 537.1, using PS2 solid-phase extraction and LC–MS/MS.
Non-targeted Analyses of PFAS
Workflows for non-targeted analyses for PFAS in wastewater and soil samples are demonstrated using a Xevo G2-XS QTof coupled with an ACQUITY UPLC.
PFAS in Drinking Water Following EPA 533
This brief demonstrates the extraction and analysis of 25 PFAS compounds from water samples using Oasis WAX for PFAS SPE cartridges, according to EPA 533 methodology.
Adapting to Challenging PFAS Analysis
Read a case study about how an environmental laboratory meets the challenges of increased sample throughput, trace detection, and complex matrices for PFAS testing.
PFAS in Serum
An application for extraction and analysis of PFAS from human serum utilizing weak anion exchange (WAX) chemistry and Xevo TQ-S micro.
PFAS Analysis Solutions Brochure
Waters has been a pioneer in PFAS analysis, providing total application solutions that include UPLC columns, sample preparation chemistry, LC–MS/MS systems, and more.
An Alternative Ionization: Unispray Source for PFAS
Unispray ionization is compared to typical electrospray for the analysis of PFAS in environmental samples.
Legacy and Emerging PFAS
A robust and reliable solution for monitoring for 40 PFAS compounds including replacements like HFPO-DA, and short-chain analytes.
Optimizing LC and LC–MS methods with better LC columns
Using fast, efficient HALO® Fused-Core® technology columns and manipulating selectivity quickly develops methods for fast, high-efficiency LC and LC–MS separations.
LC–MS Separation SAMHSA 5 Panel
This application demonstrates HALO® Biphenyl is an ideal choice for high throughput analysis of drug panels, in which isobaric species separation is needed.
Comparative LC Separation of NSAIDs
The separation of non-steroidal anti-inflammatory drugs 60% less time, with better resolution than a typical HPLC column packed with fully porous particles, is demonstrated.
A Commitment to Innovation, Quality, and Experience
This document demonstrates how AMT improves the presentation of the sample to the detector using our Fused-Core® particle design and quality manufacturing.
LC Separation of Ten Phenolic Acids
This application note demonstrates the separation of ten phenolic acids with excellent speed and resolution due to the HALO RP-Amide column.
Surmounting the Challenges of Bispecific Antibody Characterization
LC/MS of Intact Adeno-Associated Virus Capsid Proteins for Rapid Confirmation of Product Identity
Robust, Reliable, Recombinant Protein A Monolith Column for Antibody Titer Determination
Analysis of Camelid Single-Domain Antibodies Using Agilent AdvanceBio SEC 120 Å 1.9 μm and AdvanceBio HIC Columns
App Note: Characterization of Viral Vector Particles Using the Agilent 6545XT AdvanceBio LC/Q-TOF
Purification of Single-Stranded RNA Oligonucleotides Using High-performance Liquid Chromatography
Direct Analysis of PFAS in Multiple Samples
This application note demonstrates analysis at low levels (ng/L) in a wide variety of matrices for EPA 8327 method validation.
PFAS Determination in Drinking Water
This application note describes an efficient and reliable method to meet U.S. EPA Method 537.1.
Advances in UHPLC/HPLC 2021
High-Resolution Analysis of Monoclonal Antibodies Using the Cation Exchange Column BioPro IEX SF
This application note investigates the use of YMC BioPro SF for high-resolution charge variant analysis of four therapeutic mAb products.
Method Development of IEX mAb Separations Using YMC BioPro IEX Columns and Dial-a-Mix v2
The dial-a-mix method with a quaternary pump HPLC quickly screens different method conditions when developing ion-exchange methods for charge variant analysis of mAbs.
Use of YMC-Triart PEEK-Lined Columns for Improved Peak Shape of Coordination Compounds
This application note describes the benefits of using YMC-Triart PEEK-lined columns for separations involving coordination compounds.