Application Notes

Learn about residual impurities in cetyl alcohol method, according to the USP monograph, that offers enhanced compound resolution and highly repeatable injections.

PFAS experts provide insight on workflow considerations on how to manage and prevent cross-contamination to ensure quality analysis.

YMC-Triart Bio C4 is used to successfully analyze monoclonal antibodies in reversed-phase mode in this robust application.

A comprehensive selection of applications for the determination of Persistent Organic Pollutants (POPs)

In metabolomics analysis, the use of a biocompatible LC system has significant advantages over a stainless steel LC, as demonstrated in this application.

This study focuses on PEG samples having a molecular weight of less than 450 where USP specifies a GC–FID using a packed column as the analytical method of choice.

FAQ on scope, workflow, timeline, requirements for the Fith Unregulated Contaminants Monitoring Rule (UMCR 5)

This application demonstrates that YMC-BioPro IEX SF is an outstanding stationary phase for the characterization of charge variants in mAbs.

This application note demonstrates the use of YMC-Triart C18 ExRS for UHPLC potency analysis of 11 common cannabinoid compounds.

Analysis of HFPO-DA in a multi-residue method along with 24 other common PFAS

Fast method that provides excellent resolution and highly repeatable separations helping to improve data quality and increase laboratory productivity.

Achieve narrow peaks and high sensitivity by optimizing the separation of phosphorothioate oligonucleotides in 5 steps using the strong anion exchanger BioPro IEX QF.

This application note explores when to use each of YMC’s two HIC columns by comparing retention behaviors of BioPro HIC HT and BioPro HIC BF.

Analysis of volatile petrochemical hydrocarbons in the environment by fully automated workflow (flow-modulated headspace–GC×GC–FID) for efficient sample quantitation

Using GC–TOF-MS for comprehensive profiling of seized drug samples, for confident identification of controlled substances, as well as adulterants and cutting agents

Application note describing how thermal desorption–GC–MS is used to address multiple challenges in the detection of microplastics in different salt samples

This study describes the development of an analytical platform based upon TD–GC×GC–TOF-MS and shows its application to the collection and analysis of breath samples.

Characterization of pathogen-specific biomarkers in bacterial pneumonia using high-capacity sorptive extraction, thermal desorption–GC–MS, and automated chemometrics

Nontarget screening of organic pollutants in water using thin-film SPME, GC×GC, and TOF-MS to determine compositional differences in water purification treatment

SEC with multi-angle light scattering (SEC-MALS) or in conjunction with a viscometer (SEC-MALS-IV) effectively characterizes branching in polymers.

FFF combined with NTA can be used in the development of therapeutics for biological samples for the optimization process in clinical trials under in vivo conditions.

SEC–MALS quantifies biophysical attributes of mRNA, including molar mass, percent aggregates, Rg, and Rh, and how they are affected by formulation and storage conditions.

Wyatt’s instruments and techniques constitute platform methods for effective product and process development, as well as quality control of AAVs for gene therapy.