Application Notes: LC-MS

This application note covers the use of a method package to assess the safety level of several meat samples, eggs, and milk.

In this application note, an HPLC with MWD detection method is detailed to detect parabens in cosmetic and personal care products.

This application note will describe a rapid LC–MS/MS method for the separation and detection of 44 drug of abuse compounds in urine samples.

Method for complete, accurate quantification of vitamin E acetate by LC–MS/MS in less than three min, utilizing a PerkinElmer QSight® 420 triple quadrupole system

Effective, robust online SPE sample loading and chromatographic separation/quantitation of mycotoxins, using QSight SP50 online SPE system with a QSight 210 MS/MS detector.

This application note demonstrates a simple, fast, and robust green chemistry method for the accurate quantitation of six additives in diet soft drinks.

Rapid, simple LC method for the analysis of six common VOC metabolites in urine for monitoring occupational exposure to the VOCs styrene, toluene, xylene, and ethylbenzene.

In this work, an LC–MS/MS method is presented for the analysis of 66 pesticides and five mycotoxins in cannabis and hemp concentrate.

This validation study demonstrates the use of the QSight® tandem quadrupole mass spectrometer (LC–MS/MS) for the application of PFAS EPA Method 537.1 in drinking water.

LC–MS workflow for accurate quantification/detection of individual host cell proteins, from sample preparation to the reporting of values of process-related impurities.

Efficient and accurate HPLC analysis of lamotrigine in compliance with USP

USP-compliant assay analysis of hydrocortisone using a PerkinElmer LC 300 HPLC System

Efficient and compliant HPLC analysis of pregabalin

Determination of four complex carbohydrates utilizing a PerkinElmer LC 300 HPLC System, a hydrophilic interaction chromatography (HILIC) technique

HPLC method for saccharide content determination via method CRA SACCH.03 through the analysis of nine commercially available high fructose corn syrups

A review of considerations when optimizing high-throughput methods and achieving fast analyses on Avantor® ACE® HTP-MS columns with examples of key LC–MS separations.

Determination of 16 common cannabinoids utilizing a PerkinElmer LC 300 HPLC System

A robust and sensitive HPLC method with multi-wavelength UV–vis detector for the analysis of 2-phenoxyethanol and seven parabens in commercially available PCPs

USP-compliant method for determination of six isoflavone compounds in dietary supplement capsules with the PerkinElmer LC 300 UHPLC System with PDA detector

A rapid and simple LC method for the analysis of six common VOC metabolites in urine for monitoring occupational exposure to VOCs

We show the separation of tacrolimus from its related substances following Ph. Eur. monograph 2244 using the Luna 3 µm C18(2) and Luna Omega µm.

We report the separation of diazoxide and its related organic impurities using a Kinetex ™2.6 µm biphenyl column according to the USP monograph for diazoxide.

This step-by-step selectivity guide is an overview of the reversed-phase HPLC/UHPLC options available to you, highlighting the differences between the columns.

LC–UV assay and organic impurities for paliperidone drug substance based on USP monograph where a L1 (C18) column with 100 x 4.6 mm, 3 µm dimensions was used

LC–MS/MS method to separate furosemide and its metabolite using three different columns: Kinetex 2.6 µm Biphenyl, Luna Omega 1.6 µm C18, and Luna Omega 1.6 µm Polar C18

Luna Omega 1.6µm, 3µm, and 5µm HPLC/UHPLC columns culminate 20 years of technological prowess, advancements, and innovation.

Easily determine the allowable adjustments that can be made to European Pharmacopoeia (EP) methods and find the right column for your method.

Quickly view allowable adjustments outlined by the United States Pharmacopeia (USP) and select the proper Phenomenex column for your monograph using this simple guide.

Analysis of ABN7 test mix used to assess scalability for Luna Omega C18 columns across a range of particle sizes (1.6 µm, 3 µm, and 5 µm) in three different dimensions.

Improve United States Pharmacopeia (USP) method performance with allowable adjustments