Application Notes: LC-MS
PFAS Interlaboratory Study from Potable and Non-potable Water Samples
Multiple laboratories applied method EPA 537.1 and 533 for the extraction of PFAS in pristine non-potable water and source water assessment.
Managing Cross-contamination in PFAS Sampling, Extraction, and Analysis
PFAS experts provide insight on workflow considerations on how to manage and prevent cross-contamination to ensure quality analysis.
Improved Metabolomic Analysis Using an Iron-Free Flow Path
In metabolomics analysis, the use of a biocompatible LC system has significant advantages over a stainless steel LC, as demonstrated in this application.
FAQ on PFAS Unregulated Contaminants Monitoring Rule (UCMR 5)
FAQ on scope, workflow, timeline, requirements for the Fith Unregulated Contaminants Monitoring Rule (UMCR 5)
Extraction and Analysis of GenX, from Water by LC-MS/MS
Analysis of HFPO-DA in a multi-residue method along with 24 other common PFAS
Automated Extraction of Benzodiazepines from Urine
Benzodiazepines are depressants and used to relieve anxiety, insomnia, and more. This app note discusses a urine extraction to confirm the presence of benzodiazepines.
Application Note : VOC Metabolites in Urine by HPLC with UV Detection
A rapid and simple LC method for the analysis of six common VOC metabolites in urine for monitoring occupational exposure to VOCs.
Determination of Mycotoxins in Food
A fully validated method for the determination of twelve mycotoxins in various food matrices by stable isotope dilution QSight LC–MS/MS.
Fast LC–MS/MS Analysis of Amino Acids in Plasma
A fast, direct method for LC–MS/MS analysis of amino acids in plasma was developed during the course of this study.
SPE of Cannabinoids from Blood and Urine
Ultra-Robust High-Throughput Peptide Quantification (V3)
This application note shows a micro-flow LC–MS method developed on the Thermo Scientific Vanquish Neo UHPLC system is suitable for high-throughput proteomic analyses of large sample cohorts.
Ultra-Robust High-Throughput Peptide Quantification (V2)
New Standards for Bottom-up Proteomics (V3)
This application note reveals the Thermo Scientific Vanquish Neo UHPLC system offers maximal MS utilization for direct injection workflows and versatility to separate peptides at low flow rates.
New Standards for Bottom-up Proteomics (V2)
Overcome MAM deployment challenges in QC
This application note demonstrates the seamless method transfer from research and development to QC enabled by the end-to-end MAM 2.0 workflow.
Deeper mining of proteomics data
Learn how machine learning and artificial intelligence enable new capabilities in proteomics data processing to increase throughput and depth of coverage.
Label-free Proteomics with Orbitrap Exploris 480 MS
Screening and Semi-Quantitation of Fentanyl Analogs
This technical note demonstrates the screening capabilities of Thermo Scientific™ Orbitrap Exploris™ 120 mass spectrometer’s accurate analysis of 212 fentanyl compounds
High-throughput single-cell proteomics analysis
Mass spectrometry (MS) based proteomics is a promising technique for single-cell analysis by enabling the identification and quantification of thousands of proteins in an unbiased manner.
Accelerate your AAV gene therapy
New infographic to discover optimized workflows utilizing leading Thermo ScientificTM instruments, consumables, and software for AAV product and process characterization.
Infographic: Successful Grant-Writing in 7 Steps!
A well-thought-out and detailed grant proposal is essential to the success of the application. Here are 7 steps in the grant-writing process to help you reach new heights.
Ultra-sensitive LC-MS workflow
In-Depth Label-free analysis of single mammalian cells with nanodroplet single processing
LC-MS/MS Technology Advancements in Multi-residue Analysis
This document reveals integration of LC-MS with an on-line advanced mass spectral database to enable faster development of acquisition methods.
Ultra-sensitive quantification of antibody biotherapeutics and biomarkers
This App Note discusses ultra-sensitive quantification of antibody biotherapeutics and biomarkers with a novel trapping-microLC-FAIMS/SRM-MS strategy.
System performance evaluation for peptide mapping
In this new infographic, discover optimized workflows utilizing leading Thermo ScientificTM instruments, consumables, and software for AAV product and process characterization.
Comprehensive oligonucleotide analysis
Quantification of Sulfonamides in Meat Using FAIMS
App Note discusses improving the limit of quantification of sulfonamides in complex meat muscle extract by incorporating FAIMS technology into the LC/MS workflow.
LC-MS for detection of SARS-CoV-2
This technical note provides discovery to quantitation workflows for COVID-19-infected individuals by monitoring two biological matrices – plasma and nasopharyngeal swab
Authenticity of Fruit Juices by LC-MS/MS
Developing an analytical method that merges 3 conventional LC-UV methods into 1 LC-MS/MS method, improving laboratory productivity while maintaining high data confidence.
Evolution of modern single-cell proteomics
This illustration provides a brief chronology of single-cell proteomics.
