Phenomenex Expands Method Development Services
Phenomenex has announced that PhenoLogix, the company’s in-house analytical services group, has moved to an expanded, stand-alone facility. The 9000-squareâfoot laboratory has been designed to develop methods for customers in ultrahighâpressure liquid chromatography (UHPLC), LC, LC coupled to mass spectrometry (MS), and gas chromatography (GC), as well as sample preparation, impurity isolations, chiral screening and smallâ to mediumâscale purifications. PhenoLogix provides support for the company’s product line to customers in drug discovery and development, environmental testing, food safety and quality, forensics, and clinical research. PhenoLogix was cultivated from Phenomenex’s research and development department into a self-contained organization. The new facility features instruments from multiple manufacturers to address a range of applications. Sean Orlowicz, manager of PhenoLogix, commented: “From method development and transfer to understanding the nuances of current sample preparation techniques, our scientists are dedicated to customer support. We provide our services via phone or on-line communication and even at the customer site if necessary.” For more information please visit: www.phenomenex.com
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
