Peaks of Interest
The Australian Patent Office has granted a patent related to W. R. Grace & Company's (Columbia, Maryland) Reveleris flash chromatography system.
Patent Granted for Flash Chromatography Technology
The Australian Patent Office has granted a patent related to W. R. Grace & Company's (Columbia, Maryland) Reveleris flash chromatography system. The patent concerns the use of evaporative light scattering detection (ELSD) with flash chromatography. The technology covered in this allowed claim enables streamlined purification of new chemical and biological entities for drug discovery.
Grace previously received similar U.S. patents related to various aspects of flash chromatography using two kinds of detectors, such as ELSD and UV, to collect sample fractions. These techniques improve new molecule purification by increasing recovery, improving reliability, and simplifying instrument operation.
Chris Reddy Receives Award for Oil Spill Research
Chris Reddy, a marine geochemist at the Woods Hole Oceanographic Institution (WHOI) (Woods Hole, Massachusetts), has been selected to receive the 2014 Clair C. Patterson Award from the Geochemical Society. The award recognizes one scientist a year who has made an innovative breakthrough in environmental geochemistry in service to society.
Reddy was nominated for the award because of his work on developing and applying advanced chromatographic and spectrometric techniques to identify the source, transport, and fate of petroleum hydrocarbons in the coastal and open ocean. The award will be presented at Goldschmidt2014 (Sacramento, California) in June 2014.
"One of my overarching interests in studying oil spills is that there are compounds in oil that seem to persist a very long time while there are others that can disappear quickly. I find it fascinating that a spectrum like this exists," said Reddy. He added: "Clair C. Patterson was a tenacious trailblazer in studying lead and lead pollution. For me to be associated with him is, quite frankly, humbling."
Jeff Seewald, chair of WHOI's Department of Marine Chemistry and Geochemistry said: "His application and development of innovative analytical approaches have resulted in a quantum leap in our ability to predict the persistence of anthropogenic and naturally occurring petroleum in the marine environment."
Seewald added: "Chris is motivated by a strong desire to understand the consequences of human activity on the environment and has a special gift for communicating relevant information to the scientific community, policy makers, and the general public."
An LC–HRMS Method for Separation and Identification of Hemoglobin Variant Subunits
March 6th 2025Researchers from Stanford University’s School of Medicine and Stanford Health Care report the development of a liquid chromatography high-resolution mass spectrometry (LC–HRMS) method for identifying hemoglobin (Hb) variants. The method can effectively separate several pairs of normal and variant Hb subunits with mass shifts of less than 1 Da and accurately identify them in intact-protein and top-down analyses.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
