Addressing Chemical Diversity and Expanding Analytical Capabilities with Atmospheric Pressure GC
Atmospheric pressure gas chromatography is a technique that allows rapid switching between UPLC-MS and GC-MS applications.
Atmospheric pressure gas chromatography (APGC) is a technique that allows rapid switching between UPLC-MS and GC-MS applications. This provides laboratories with the flexibility to analyse volatile and semi-volatile compounds of low and intermediate polarity traditionally analysed by dedicated vacuum GC-MS instruments. Changeover of the electrospray source requires minimal tools, no breaking of vacuum and typically less than 5 minutes to perform. It is possible to acquire data in ESI+ using UPLC separation, then within 1 hour, review data acquired using APGC on the same instrument (assuming a typical GC run time of 25-30 min). This type of procedure can be particularly valuable when screening samples prepared using generic techniques such as QuEChERS, which can generate extracts amenable to both UPLC and GC separations.
RAFA 2024 Highlights: Contemporary Food Contamination Analysis Using Chromatography
November 18th 2024A series of lectures focusing on emerging analytical techniques used to analyse food contamination took place on Wednesday 6 November 2024 at RAFA 2024 in Prague, Czech Republic. The session included new approaches for analysing per- and polyfluoroalkyl substances (PFAS), polychlorinated alkanes (PCAS), Mineral Oil Hydrocarbons (MOH), and short- and medium-chain chlorinated paraffins (SCCPs and MCCPs).
Advancing Bladder Cancer Research with Mass Spectrometry: A FeMS Interview with Marta Relvas-Santos
November 12th 2024LCGC International interviewed FeMS Empowerment Award winner Marta Relvas-Santos on her use of mass spectrometry to identify potential biomarkers and therapies for bladder cancer. She also shared insights on her work with FeMS and advice for fellow scientists.
