Squalene and squalane are oils, often used in the production of cosmetics and vaccines. Originally derived from the liver oil of deepwater sharks, squalane is also available from olives, and since 2008 some important cosmetic firms have claimed to switch to this more ethical squalane supply. However, the shark oil offers a higher yield and lower costs, so suppliers face the temptation to disguise the oil?s origin, while continuing to exploit sharks. A method in Rapid Communications in Mass Spectrometry is reported to reveal the source, protecting sharks, as well as cosmetic firms and consumers.
Squalene and squalane are oils, often used in the production of cosmetics and vaccines. Originally derived from the liver oil of deepwater sharks, squalane is also available from olives, and since 2008 some important cosmetic firms have claimed to switch to this more ethical squalane supply. However, the shark oil offers a higher yield and lower costs, so suppliers face the temptation to disguise the oil’s origin, while continuing to exploit sharks. A method in Rapid Communications in Mass Spectrometry is reported to reveal the source,1 protecting sharks, as well as cosmetic firms and consumers.
The method uses an isotope ratio mass spectrometer coupled to an elemental analyser or gas chromatography/combustion system to measure the ratio of carbon-13 and carbon-12. The carbon-13/carbon-12 ratios were significantly lower in authentic olive oil than in shark samples, providing a method to distinguish between the two.
“Our method will protect both cosmetic firms and consumers from commercial fraud. It will also allow the origin of squalane within a finished product to be determined,” said Federica Camin, who works at the IASMA Research and Innovation Centre Fondazione Edmund Mach, in San Michele all’Adige, Italy and was one of the authors of the article. “Together, this will discourage the illegal fishing of deepwater sharks and thus contribute towards protecting sharks from the threat of extinction.”
1. F. Camin et al., Rapid. Commun. Mass Spectrom., on-line 19 May 2010.
This story originally appeared in The Column. Click here to view that issue.
Understanding FDA Recommendations for N-Nitrosamine Impurity Levels
April 17th 2025We spoke with Josh Hoerner, general manager of Purisys, which specializes in a small volume custom synthesis and specialized controlled substance manufacturing, to gain his perspective on FDA’s recommendations for acceptable intake limits for N-nitrosamine impurities.
University of Rouen-Normandy Scientists Explore Eco-Friendly Sampling Approach for GC-HRMS
April 17th 2025Root exudates—substances secreted by living plant roots—are challenging to sample, as they are typically extracted using artificial devices and can vary widely in both quantity and composition across plant species.
Determining the Serum Proteomic Profile in Migraine Patients with LC–MS
April 17th 2025Researchers used liquid chromatography–mass spectrometry (LC–MS) in their proteomic analysis to compare the serum proteome of migraine patients with healthy controls and to identify differentially expressed proteins as potential migraine biomarkers.
Understanding FDA Recommendations for N-Nitrosamine Impurity Levels
April 17th 2025We spoke with Josh Hoerner, general manager of Purisys, which specializes in a small volume custom synthesis and specialized controlled substance manufacturing, to gain his perspective on FDA’s recommendations for acceptable intake limits for N-nitrosamine impurities.
University of Rouen-Normandy Scientists Explore Eco-Friendly Sampling Approach for GC-HRMS
April 17th 2025Root exudates—substances secreted by living plant roots—are challenging to sample, as they are typically extracted using artificial devices and can vary widely in both quantity and composition across plant species.
Determining the Serum Proteomic Profile in Migraine Patients with LC–MS
April 17th 2025Researchers used liquid chromatography–mass spectrometry (LC–MS) in their proteomic analysis to compare the serum proteome of migraine patients with healthy controls and to identify differentially expressed proteins as potential migraine biomarkers.