Solid-Phase Extraction (SPE)

New MSPE-CE-DAD study indicates that efficiency remained above 75% even when a magnetic solid-phase extraction (MSPE) method was repeated five times, noting that the magnetic porous carbon (MPC) used in the extraction can be easily recycled.

Eighty drugs prohibited in athletic competition were analyzed, with seven samples returning adverse findings compared to previous methods.

A new method determines gas-polydimethylsiloxane (PDMS) distribution constants of key Cannabis terpenes and terpenoids, providing insights into their behavior and for optimizing SPME methods for analysis of these compounds.

This month we interview Juan L. Benedé from the University of Valencia in Spain, about his work developing microextraction approaches, based on the use of sorbent materials, for application to complex matrices, and his focus on the determination of disease biomarkers in biofluids.

A team of researchers from the University of Barcelona has developed a new method for the selective extraction of monosaccharide anhydrides from sediment samples, which is crucial for their analysis.

A solid-phase microextraction (SPME) Arrow combined with comprehensive two-dimensional gas chromatography coupled to mass spectrometry (GC×GC–MS) identified about 40 more volatile compounds in a variety of whiskeys compared to conventional SPME.

Scientists have developed a magnetic ionic liquid hypercrosslinked polymer composite for use in magnetic solid-phase extraction (MSPE) of non-steroidal anti-inflammatory drugs (NSAIDs), which was coupled with high-performance liquid chromatography (HPLC) for the detection of trace amounts of NSAIDs in water and urine samples.

Exploring the impact of green chemistry on analytical chemistry and GC is the focus of this instalment of "GC Connections".

This yearly report on new products introduced at Pittcon and in the preceding year covers sample preparation instruments, supplies, and accessories.

Direct-injection mass spectrometry (DIMS) and gas chromatography (GC) approaches have some significant differences that are pertinent when analyzing volatile organic compounds (VOCs). We explain.

Everyone is talking about sustainability, and organizations are creating sustainability programs. But what does green chemistry really mean, and how does it apply to gas chromatography?

Here's the scoop on the latest offerings in sample preparation.

Pesticides in local surface and groundwaters were purified and enriched with solid-phase extraction, then analyzed using multidimensional gas chromatography coupled to mass spectrometry, with the results compared to those found by gas chromatography–quadrupole mass spectrometry.

The development of antibiotics needs to constantly be evolving to counter bacterial resistance that can develop against these medications. Solid-phase extraction (SPE) can be used to combat this challenge.

Solid-phase extraction holds an important role in identifying and improving the effectiveness of antibiotics.

Solid-phase microextraction combined with mass spectrometry improves our ability for rapid drug screening.

The 25th edition of the International Symposium on Advances in Extraction Technologies (ExTech) will be held in Tenerife (Canary Islands, Spain) from 18–21 July 2023. Here’s a glimpse of what attendees can look forward to.

Online SPE–LC–MS/MS combined with the method presented enabled automated cleanup of food extracts and determination of PFAS compounds in the ng/kg range.

How to speed up sample prep time and equivalent acccuracy and precision.

A GC–MS method, coupled with magnetic SPE with multi-walled carbon-nanotube (MWCNT)-coated iron oxide as the adsorbent, was developed for analyzing organophosphate esters in environmental water samples.

Reducing matrix effects during LC–MS/MS bioanalysis is paramount. Improving sample preparation techniques is the best way to combat this issue.

Multiple-cumulative trapping headspace extraction coupled with high-concentration-capacity tools, such as SPME, enhances sensitivity of volatiles, as illustrated here in food analysis.

We look at five modern treatments of chromatographic sample extraction, explaining their initial conception and development to shed light on their current roles as analytical tools.

This symposium looks at various methods used to detect PFAS in foods, cosmetics, packaging, and commercial products.

The Dal Nogare award honors an awardee who is selected for contributions to the fundamental understanding of the chromatographic process. This year’s award winner is Professor Apryll Stalcup from Dublin City University.

Currently, sample treatment is still the bottleneck in the development of analytical methods to analyze complex samples, especially for routine analysis where high-tech instruments are not always available. Research on the evaluation of different sample treatments is needed to achieve the sensitivity and selectivity required. This article presents a case study related to the determination of sulphonamides in liver. Different extraction strategies, including solid-liquid extraction (SLE), ultrasound-assisted extraction (UAE), and solid-phase extraction (SPE), were evaluated to produce a simple and effective extraction method.

HS-SPME-GC–MS is a valuable technique for identifying volatile organic compounds, additives, and degradation products in industrial rubber, car labeling reflection foil, and bone cement materials.

An excerpt from LCGC’s e-learning tutorial on common solid-phase extraction (SPE) problems at CHROMacademy.com

Tips and tricks to help you recognize and solve the most common SPE problems.

A solid phase microextraction (SPME) method was developed using a new overcoated PDMS–DVB fiber for immersion extraction of pesticide residues from spaghetti sauce. The overcoating, which consisted of polydimethylsiloxane, offered protection to the SPME fiber, making it more resistant to physical and chemical damage. Also, it increased fiber selectivity for the smaller analyte molecules over macromolecules present in sample matrix. This then allowed it to be used in immersion extraction of a very complex matrix-spaghetti sauce. Performance of the overcoated fiber was compared to a nonovercoated fiber of the same chemistry for method accuracy, precision, and durability. The SPME method developed using the overcoated fiber was then compared to extraction of the same pesticides in spaghetti sauce using a conventional QuEChERS method for extraction and cleanup. SPME was comparable to the QuEChERs method for both accuracy and precision. However, its main advantage over QuEChERS was in sensitivity and method simplicity.