Vol 36 No 8 LCGC North America August 2018 Regular Issue PDF
Click the title above to open the LCGC North America August 2018 regular issue in an interactive PDF format.
The Vital Role of Blanks in Sample Preparation
Blanks are important in the pursuits of quality control and robust quantitative analytical methods, but many analysts don’t fully understand their value, or how to use them correctly.
Contaminants Everywhere! Tips and Tricks for Reducing Background Signals When Using LC–MS
We examine instances where contaminants are problematic in LC–MS, as well as successful methods to decrease their influence.
Ten Common-Sense Corollaries in Pharmaceutical Analysis by HPLC
These ten propositions are widely acknowledged, but frequently neglected, by practitioners of high performance liquid chromatography (HPLC).
Advantages of Supported Liquid Extraction
We look at a process that can overcome the shortcomings associated with liquid–liquid extraction.
Biomimetic Chromatography to Accelerate Drug Discovery: Part II
Biomimetic HPLC retention data can be used to measure how a compound will bind to proteins and phospholipids in vivo.
Frontiers in Ultrafast Chiral Chromatography
We explore the developments that have made it possible to produce sub-minute, and, more recently, even sub-second enantiomeric separations. We also look at the questions that remain unanswered.
Data Integrity in the Chromatography Laboratory, Part V: Second-Person Review
The series continues with a crucial scientific and regulatory necessity in ensuring reliable information-the second-person review.
Chromatography Fundamentals, Part IV: Origin of Theoretical Plates—Fractional Distillation and Countercurrent Distribution Extractions
The theoretical plate concept forms the basis of chromatographic theory. Here is where it came from.
