James Martosella

James Martosella is an R&D Scientist, Bioseparations, Agilent Technologies, Little Falls, Delaware.

Articles

Increasing Speed for Biocharacterizations: Peptide Mapping ofMonoclonal Antibodies with an Agilent AdvanceBio Peptide Mapping Column

Alex Zhu;James Martosella

December 2nd 2013

Agilent Technologies

Peptide Mapping of Glycoprotein Erythropoietin by HILIC LC–MS and RPLC–MS

Alex Zhu;Phu T. Duong;James Martosella

July 2nd 2013

Agilent Technologies, Inc

High Resolution Glycopeptide Mapping of EPO Using an Agilent AdvanceBio Peptide Mapping Column

James Martosella;Phu T. Duong

March 2nd 2013

Agilent Technologies Inc.

New Sample Fractionation Strategies for Proteomic Analyses by LC–MS

Robert Kincaid;James Martosella;Peter Mrozinski;Jerome Bailey;Christine A. Miller;Tobias Preckel

November 1st 2006

Mass spectrometry has long been a preferred tool for protein identification and biomarker discovery, but preparation of biological samples remains a challenge. Hindrances include the wide range of protein concentrations, sample complexity, and loss or alteration of important proteins due to sample handling. This article describes recent developments in sample fractionation technologies that are overcoming these challenges in interesting ways and are enabling in-depth proteomic studies that were not possible in the past.