Application Notes: Food and Beverage

SPE is used in combination with LC–MS/MS to analyze a panel of opiates from a urine sample.

Optimize the LC–MS/MS workflow by using a SPE solution that provides in-well urine hydrolysis to save time.

Optimize the LC–MS/MS workflow by using a SPE solution that provides in-well urine hydrolysis to save time.

A reliable and efficient method was developed to determine the concentration sterols in olive oil by GC-FID.

Potency testing in marijuana-infused edibles is a problematic task due to the complexity of the matrices. The concentration of active ingredients in edibles can range from a few ppm to 3.5% (1). In this application, active cannabinoid compounds were extracted from gummy bears (and also brownies, results not shown), followed by HPLC analysis.

This method showed excellent precision and accuracy for the 12 FDA regulated mycotoxins that were evaluated during a validation study that covered a variety of matrices.

Organic arsenic compounds added to feed stocks of chicken and poultry pose serious environmental and ecological threats. National and worldwide health organizations, such as the U.S. Environmental Protection Agency and the U.S. Food and Drug Administration, have recently implemented more stringent concentration limits for arsenic species in drinking water and foodstuffs.

Living organisms (yeast and bacteria) were not identified as the agents that produced or spoiled common food items until the 19th century. Baking, especially of bread, was among the first industries to be transformed by the emerging scientific understanding of fermentation. The introduction of commercialized yeast in the early 20th century steadily reduced the time needed to bake bread both at home and on the production line, making way for modern packaged breads.

This method showed excellent precision and accuracy for the 12 FDA regulated mycotoxins that were evaluated during a validation study that covered a variety of matrices.

Pickering Laboratories developed an analytical method to comply with all the chromatographic requirements of Commission Regulation (EC) No 152-2009.

Sensitive detection of more than 250 pesticide residues in foods using the Agilent Ultivo Triple Quadrupole LC/MS system

Sensitive detection of more than 250 pesticide residues in foods using the Agilent Ultivo Triple Quadrupole LC/MS system

Analysis of paralytic shellfish toxins using a HPLC single step-gradient method with products of post-column derivatization detected using a fluorescence detector

The easy to use, new LipiFiltr® push-through purification cartridge was designed to remove lipids from acetonitrile extracts. This application will outline the performance benefits achieved using the new LipiFiltr® cartridges in applications involving multiclass, multiresidue analysis for pesticides in complex, high fat samples.

In this study, a fast, sensitive, and selective multiresidue method has been developed by coupling QuEChERS sample preparation with LC–MS/MS. Using time-managed-MRM™ in the QSight® triple quadrupole mass spectrometer, the optimum dwell time can be generated automatically for MRM transitions based on the number of coeluting transitions, expected cycle time, retention time, and tolerance time window of the targeted analytes. Such method automation results in improved data quality and better sensitivity, accuracy, and reproducibility, as demonstrated in this study by the results of 213 pesticide residues analyzed in grape samples.

The building blocks of peptides and proteins, amino acids, are present in animals, humans, and plants. The analysis of amino acids is of essential significance in several areas including food science, clinical diagnostics, and pharmaceutical products research. Classical liquid chromatography (LC) determination of amino acids is performed with sample pretreatment including pre-column as well as post-column derivatization to improve or enable spectroscopic detection.

A sensitive determination method with automated solid‑phase extraction (SPE) is presented and the recovery rates are compared with manual extraction. The automated extraction was developed with the SPE robot FREESTYLETM SPE module (LCTech GmbH). According to the European Regulation (EC) No 470/2009, CHROMABOND® HLB was applied for SPE (1). A high performance liquid chromatography tandem mass spectrometry (HPLC–MS/MS) method with the biphenyl phase NUCLEODUR® π2 was used for the subsequent analysis.