Spectral Quality and Reproducibility in Thermal Modulation Comprehensive GCxGC-MS Mass Spectrometer Using a Rapid Scanning Quadrupole
The Column
Invented by J. Phillips in 1989, comprehensive GCXGC has strong chromatographic resolving power; from its original petrochemical applications it has been extended to many others. However, coelutions with matrix peaks are often observed and a higher separation power is required.
Invented by J. Phillips in 1989, comprehensive GC×GC has strongchromatographic resolving power; from its original petrochemicalapplications it has been extended to many others. However, coelutionswith matrix peaks are often observed and a higher separation power isrequired. The coupling of GC×GC to mass spectrometry (MS) providesan additional dimension for the identification of compounds concealedunder contour plot displays used in GC×GC.
Detangling the Complex Web of GC × GC Method Development to Support New Users
November 1st 2024In this article, the authors describe a simple workflow to develop a GC×GC method for a specific sample upon initial use, with the aim of decreasing the time to accomplish functional workflows for new users.
