Taking Advantage of Sub-2μm Core-Shell Particles for Ultra-Fast and Efficient Urinary Excretion Profiling

Article

The Column

ColumnThe Column-10-24-2012
Volume 8
Issue 19
Pages: 14–17

Urinary excretion profiling is a key element in the pharmokinetic characterization of new chemical entities (NCEs). Recent advances in ultra-high performance liquid chromatography (UHPLC) column technology offer improved results for liquid chromatography tandem mass spectrometry (LC–MS¬–MS) analysis, enabling rapid quantification of specific drugs and their metabolites in biological matrices.

Urinary excretion profiling is a key element in the pharmokinetic characterization of new chemical entities (NCEs). Recent advances in ultra-high performance liquid chromatography (UHPLC) column technology offer improved results for liquid chromatography tandem mass spectrometry (LC–MS) analysis, enabling rapid quantification of specific drugs and their metabolites in biological matrices.

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Articles in this issue
Holistics evidence
Taking Advantage of Sub-2μm Core-Shell Particles for Ultra-Fast and Efficient Urinary Excretion Profiling
Taking Advantage of Sub-2μm Core-Shell Particles for Ultra-Fast and Efficient Urinary Excretion Profiling
Spectral Quality and Reproducibility in Thermal Modulation Comprehensive GCxGC-MS Mass Spectrometer Using a Rapid Scanning Quadrupole
Spectral Quality and Reproducibility in Thermal Modulation Comprehensive GCxGC-MS Mass Spectrometer Using a Rapid Scanning Quadrupole
Petrochemical Profiling
Petrochemical Profiling
Lethal bite
Hydrogel delivery
Fishing for antidotes
Back to the Start
Back to the Start
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Exploring Molecular Dynamics: An Interview with Ezgi Gürler of FeMS
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Developing Advanced Fragmentation Schemes: An Interview with Ezgi Gürler of FeMS
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