Preparative Chiral SFC as a Green Technology for Rapid Access to Enantiopurity in Pharmaceutical Process Research

Article

LCGC Europe

LCGC EuropeLCGC Europe-05-01-2005
Volume 18
Issue 5
Pages: 264–272

This month’s column provides an overview of green chemistry issues relating to preparative chiral SFC chromatography in support of preclinical development in the pharmaceutical industry.

External Link - article-159011.pdf

Articles in this issue
The Bermuda Triangle
Preparative Chiral SFC as a Green Technology for Rapid Access to Enantiopurity in Pharmaceutical Process Research
A Question of Time (and Date)
What’s in a Method
PeakMaster — A Freeware Simulator of Capillary Zone Electrophoresis
Choice of Buffer for the Analysis of Basic Peptides in Reversed-Phase HPLC
Recent Videos
Toby Astill | Image Credit: © Thermo Fisher Scientific
Related Content
Best of the Week: J.P. Morgan Healthcare Conference, Detecting Water Pollutants with ML, Lavender’s Effects on Tumors

Best of the Week: J.P. Morgan Healthcare Conference, Detecting Water Pollutants with ML, Lavender’s Effects on Tumors

Aaron Acevedo
January 17th 2025
Article

Here is some of the most popular content posted on LCGC International this week.

Extreme macro of polyester stable fiber on blue background. Selective focus, shallow depth of field. Abstract dreamy background | Image Credit: © Taigi - stock.adobe.com

SPE-Based Method for Detecting Harmful Textile Residues

Aaron Acevedo
January 14th 2025
Article

University of Valencia scientists recently developed a method using solid-phase extraction (SPE) followed by high-performance liquid chromatography coupled to high-resolution mass spectrometry (HPLC–HRMS/MS) for detecting microplastics and other harmful substances in textiles.

herbal medicine | Image Credit: © Kwangmoozaa - stock.adobe.com

Detecting Fraudulent Substances Using Flow Injection Analysis–Mass Spectrometry

Aaron Acevedo
January 13th 2025
Article

Spanish scientists recently tested flow injection analysis–mass spectrometry (FIA–MS) and its effectiveness in detecting fraudulent substances in Coleus forskohlii food supplements.

Best of the Week: Reunifying Separation Science, Top Content of 2024, Shimadzu’s 150th Anniversary

Best of the Week: Reunifying Separation Science, Top Content of 2024, Shimadzu’s 150th Anniversary

Aaron Acevedo
January 10th 2025
Article

Here is some of the most popular content posted on LCGC International this week.

Drug addiction. Syringe and pills on wooden table, closeup | Image Credit: © New Africa - stock.adobe.com

Detecting Amphetamine-Type Stimulants with Solid-Phase Microextraction

Aaron Acevedo
January 8th 2025
Article

Jiangsu Police Institute scientists recently created a solid-phase microextraction (SPME)-based method for determining amphetamine-type stimulants.

Bags of yellow fresh frpzen plasma ready for transfusion. | Image Credit: © pirke - stock.adobe.com

New Extraction Technique Tested on Polar Metabolites in Human Plasma

Aaron Acevedo
January 7th 2025
Article

University of Oslo scientists combined electromembrane extraction (EME) and flow injection-MS/MS (FI–MS/MS) to determine polar endogeneous metabolites in human plasma.