Peaks of Interest
Thermo, Chata, and Cerno take top awards - Bruker Biosciences to acquire Bruker Optics - Chinese pharmaceutical company selects Thermo - DataApex and Knauer annouce cooperation.
Thermo, Chata, and Cerno take top awards
Thermo Electron's (Waltham, Massachusetts) Finnigan Orbitrap mass spectrometer for small molecule research, drug discovery, proteomics, metabolite identification, and metabolomics was presented with the Editor's Choice award at Pittcon 2006 in Orlando, Florida.
Chata Biosystems' (Fort Collins, Colorado) Chem+Mix prepackaged HPLC mobile phases was presented with the silver plaque, and Cerno Bioscience's (Danbury, Connecticut) MassWorks acquisition software was presented with the Bronze plaque.
Honorable mentions included the model 1200 HPLC system from Agilent Technologies (Palo Alto, California), the 800 Mhz UltraShield Plus from Bruker Daltonics (Billerica, Massachusetts), the DyanPro Plate Reader from Wyatt Technology (Santa Barbara, California), the Labworks LIMS 5.9 from PerkinElmer (Shelton, Connecticut), and the Varian 500 APCI LC–MS system from Varian (Palo Alto, California).
Bruker BioSciences to acquire Bruker Optics
Bruker BioSciences (Billerica, Massachusetts) announced that it will acquire all of the stock of molecular spectroscopy company Bruker Optics Inc. (Billerica, Massachusetts) for $135 million. The agreement was signed following its unanimous approval by a special committee of independent directors.
The combined company will have a broad range of mass spectrometry, x-ray analysis, and molecular spectroscopy technology platforms to provide a combination of complementary systems for chemical and materials analysis. It will be a provider of instrumentation and molecular analysis solutions for a variety of industries including pharmaceutical and biotechnology research and development, proteomics and structural biology, and small molecule chemical analysis.
The acquisition is expected to be immediately accretive to Bruker BioSciences' 2006 and 2007 EPS.
Chinese pharmaceutical company selects Thermo
Thermo Electron announced that WuXi PharmaTech Co., Ltd. (Shanghai, China) has selected Watson LIMS to meet the specific data management requirements of its bioanalytical facilities.
WuXi PharmaTech serves many top pharmaceutical companies and biopharmaceutical companies in the world. The company provides discovery and development services, from lead identification to pre-clinical.
DataApex and Knauer announce cooperation
DataApex (Prague, Czech Republic) and Knauer (Berlin, Germany) recently announced signature of an OEM software agreement. Knauer will market an OEM version of DataApex's product Clarity Chromatography Software under the name ClarityChrom.
All of Knauer's Smartline instruments for analytical HPLC will be supported in the first release of ClarityChrom, planned for the second half of 2006.
Analyzing Bone Proteins in Forensic Laboratories Using LC−MS/MS
November 4th 2024A recent study compared different workflows for extracting, purifying, and analyzing bone proteins using liquid chromatography with tandem mass spectrometry (LC–MS/MS), including an in-StageTip protocol previously optimized for forensic applications, and two protocols using novel suspension-trap technology (S-Trap) and different lysis solutions. LCGC International discussed this work with Noemi Procopio of the School of Law and Policing and the Research Centre for Field Archaeology and Forensic Taphonomy at the University of Central Lancashire (UK), corresponding author of the paper that resulted from this study.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
Profiling Volatile Organic Compounds in Whisky with GC×GC–MS
November 1st 2024Researchers from Austria, Greece, and Italy conducted a study to analyze volatile organic compounds (VOCs) present in Irish and Scotch whiskys using solid-phase microextraction (SPME) Arrow with comprehensive two-dimensional gas chromatography coupled to mass spectrometry (GC×GC–MS) to examine the organoleptic characteristics that influence the taste of spirits.
