The growing importance of biotherapeutics to the pharmaceutical industry has created an increasing demand for protein analysis techniques with high precision, high sensitivity and high throughput.
The growing importance of biotherapeutics to the pharmaceutical industry has created an increasing demand for protein analysis techniques with high precision, high sensitivity and high throughput. These techniques are used throughout the development process, starting with the discovery phase and continuing into lead optimization and characterization, preclinical and clinical trials (for both the biotherapeutic itself and related protein biomarkers) and manufacturing process development and control.
Separating Impurities from Oligonucleotides Using Supercritical Fluid Chromatography
February 21st 2025Supercritical fluid chromatography (SFC) has been optimized for the analysis of 5-, 10-, 15-, and 18-mer oligonucleotides (ONs) and evaluated for its effectiveness in separating impurities from ONs.