Digital Update
Chromatography software update; GPC/SEC software instrument control; Light Scattering webinars; Metabolomics Library
Chromatography software update
DataApex has released the update of its chromatography software. Clarity version 2.7 brings new control drivers covering Hitachi LaChrom Elite HPLC system (L-2100/2130 pump, L-2200 autosampler, L-2300 Column Oven, L-2400 UV Detector) and the HTA autosampler HT800L. The software can now control more than 250 instruments, according to the company. The new version enhances several functionalities that bring users more comfort during installation and configuration. The update is available for current users free of charge. The demonstration version and the complete list of controlled instruments can be downloaded from the company's website. www.dataapex.com
GPC/SEC software instrument control
Polymer Standards Services has introduced a macromolecular chromatography data system for all GPC/SEC applications. WinGPC Unity is reported to allow data acquisition from instruments and adds viscometry and light scattering detection as well as copolymer analysis, 2D chromatography and semi-preparative or high speed GPC/SEC.
The list of controlled systems has now been expanded to include Waters, Shimadzu and Dionex instruments to the existing controls for PSS SECcurity GPC systems, Agilent 1100/1200 systems and Tosoh EcoSEC systems. Instrument control is added with the SystemPilot, which provides all important functions for traceability of measurements and for documentation of system performance, as well as allowing flexible method changes and convenient gradient control for the analysis of complex polymers with LAC (Polymer HPLC). www.polymer.de
Light Scattering webinars
Wyatt Technology has announced the introduction of a programme of free-of-charge, on-demand webinars about light scattering and related technologies. Designed to meet the increasing demand for scientific training on macromolecular characterization instrumentation, the online webinar series is reported to provide comprehensive information about the company's light scattering products and services. Current webinars are available on high-throughput automated dynamic light scattering using the DynaPro Plate Reader, characterizing protein–protein interactions with static light scattering and the Calypso automated protein association and aggregation system, characterizing protein conjugates and their aggregates by light scattering and field flow fractionation combined with multi-angle light scattering. www.wyatt.com
Metabolomics Library
LECO has released the LECO/Fiehn Metabolomics Library. When combined with the Pegasus HT GC–TOF-MS, TruTOF HT GC–TOFMS or Pegasus 4D GC×GC–TOFMS and ChromaTOF software, the company claims it becomes a tool for metabolite identification. More than 1100 spectra of 700 unique metabolites are contained within the library, along with retention indices based on a series of fatty acid methyl esters, according to the company. The library is fully integrated within ChromaTOF, working with the software's Library Search feature to automatically search for possible analyte matches without importing or exporting data. Developed through a unique partnership with Dr Oliver Fiehn, this extensive and expandable library was obtained using a Pegasus GC–TOF-MS at Dr Fiehn's own laboratory at the University of California-Davis. www.leco.com
New Study Uses MSPE with GC–MS to Analyze PFCAs in Water
January 20th 2025Scientists from the China University of Sciences combined magnetic solid-phase extraction (MSPE) with gas chromatography–mass spectrometry (GC–MS) to analyze perfluoro carboxylic acids (PFCAs) in different water environments.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ion used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
A Guide To Finding the Ideal Syringe and Needle
January 20th 2025Hamilton has produced a series of reference guides to assist science professionals in finding the best-suited products and configurations for their applications. The Syringe and Needle Reference Guide provides detailed information on Hamilton Company’s full portfolio of syringes and needles. Everything from cleaning and preventative maintenance to individual part numbers are available for review. It also includes selection charts to help you choose between syringe terminations like cemented needles and luer tips.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Oasis or Sand Dune? Isolation of Psychedelic Compounds
January 20th 2025Magic mushrooms, once taboo, have recently experienced a renaissance. This new awakening is partially due to new findings that indicate the effects of psilocybin, and its dephosphorylated cousin psilocin may produce long lasting results for patients who might be struggling with anxiety, depression, alcohol and drug abuse, and post-traumatic stress disorder. Hamilton Company has developed a methodology for the isolation and identification of 5 common psychedelic compounds used in the potential treatment of disease. The PRP-1 HPLC column resin remains stable in the harsh alkaline conditions ideal for better separations.
