Determination of Phthalate Esters in Childcare Products and Children's Toys by GC-MS
In this article we look at the determination of phthalate esters in childcare products and children's toys by GC-MS.
The Consumer Product Safety Improvement Act of 2008 (CPSIA) requires testing of childcare products and toys for selected phthalate esters by gas chromatography–mass spectrometry (GC–MS). The CPSC test method “CPSC-CH-C1001-09.2 Standard operating procedure for Determination of Phthalate” specifies GC–MS analysis in the SIM mode to monitor for low-intensity ions unique to specific phthalate esters, but full-scan mass spectra are also valuable in qualitative identification. Operation of the mass spectrometer in the FASST Scan/SIM mode allows concurrent high speed acquisition of full-scan and SIM mass spectral data to provide improved qualitative identification while still maintaining optimum sensitivity.
RAFA 2024 Highlights: Contemporary Food Contamination Analysis Using Chromatography
November 18th 2024A series of lectures focusing on emerging analytical techniques used to analyse food contamination took place on Wednesday 6 November 2024 at RAFA 2024 in Prague, Czech Republic. The session included new approaches for analysing per- and polyfluoroalkyl substances (PFAS), polychlorinated alkanes (PCAS), Mineral Oil Hydrocarbons (MOH), and short- and medium-chain chlorinated paraffins (SCCPs and MCCPs).
Pharmaceutical excipients, such as polyethylene glycol-based polymers, must be tested for the presence of ethylene oxide (EtO) and 1,4-dioxane as part of a safety assessment, according to USP Chapter <228>.
