Researchers have found evidence that some of the building blocks of DNA that have been found in carbon-rich meteorites, may have been created in space and could have provided a molecular kit for the origins of life on Earth
Researchers have found evidence that some of the building blocks of DNA that have been found in carbon-rich meteorites, may have been created in space and could have provided a molecular kit for the origins of life on Earth.All life on Earth depends on DNA and RNA that use pyrimidine and purine nucleobases to encode genetic information. Carbon‑rich meteorites may have been important sources for some of the organic compounds of life on Earth; however, the origin and formation of nucleobases in meteorites has been debated for some time.
A team of NASA-funded researchers investigated the abundance and distribution of nucleobases and nucleobase analogues in formic acid extracts of 12 different meteorites by liquid chromatography–mass spectrometry.1The Murchison and Lonewolf Nunataks 94102 meteorites were found to contain a diverse suite of nucleobases, including three unusual and terrestrially rare nucleobase analogues. These terrestrially rare analogues were not detected above parts-per-billion detection limits in any of the procedural blanks, control samples, a terrestrial soil sample or an Antarctic ice sample.
The study suggests that this supports the idea that the analogues were produced extraterrestrially, with the asteroids producing many variants of the nucleobases, rather than just the commonly occurring biological ones. As part of the study the researchers were also able to demonstrate plausible non-biological mechanisms for their synthesis, further supporting an extraterrestrial origin.
This story originally appeared in The Column. Click here to view that issue.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
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