Designed for purification and engineered for science, Gilson, Inc. provides high quality, dependable purification solutions for your demanding liquid chromatography, solid phase extraction, liquid handling and gel permeation chromatography clean-up requirements.
Designed for purification and engineered for science, Gilson, Inc. provides high quality, dependable purification solutions for your demanding liquid chromatography, solid phase extraction, liquid handling and gel permeation chromatography clean-up requirements. From our pipetting products to a full range of HPLC system solutions focusing on purification to the broadest automated SPE and GPC clean-up solutions, Gilson is the element of purification for your laboratory.
Gilson was established in the 1940s, when Dr. Gilson, while a faculty member at the University of Wisconsin Medical School, began to design and develop specialized medical electronics and instruments that were not commercially available. One of his first efforts produced a Cathode Ray Recorder, an 18" moving paper camera to record images from a cathode ray tube. It was later used around the world in cardiac catheterization labs. By the early 1950s, Gilson was developing electroencephalographs, oxygraphs and physiological recorders.
Gilson has worldwide sales and service supporting the pharmaceutical, biotech, environmental, clinical, and food markets. Our primary focus is on purifying samples via preparative HPLC, automated SPE or through GPC clean-up. Gilson complies with early drug discovery and development through our preparative HPLC systems. And the Gilson automated SPE systems are focused on supporting environmental, food and clinical markets with our GPC clean-up systems targeted on the environmental and food markets performing a wide variety of clean-up applications.
Gilson, Inc. world headquarters is located in Middleton, WI and is responsible for research, development and manufacturing of all Gilson instrumentation and software in addition to providing direct sales to the U.S. for all Gilson Pipetting (manual liquid handling) products. Gilson S.A.S., located outside of Paris, France is responsible for all development and manufacturing of Gilson Pipetting products. Gilson International B.V., located in Netherlands, provides Gilson sales and support to the European countries.
Dan Maffet
Gilson, Inc.
Middleton, Wisconsin
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.