Nano LC: Principles, Evolution, and State-of-the-Art of the Technique
Nano LC is now widely applied in proteomics, and also is robust enough for application in fields such as pharmaceutical analysis.
Laser Diode Thermal Desorption Tandem Mass Spectrometry for Simultaneous Quantitation of Metformin and Sitagliptin in Mouse and Human Dried Blood Spots
An exploration of LDTD-MS-MS and how it compares to HPLC–MS-MS techniques in terms of sensitivity, robustness, and speed in an in-vivo drug discovery application
A Systematic Study of Achiral Stationary Phases Using Analytes Selected with a Molecular Diversity Model
A limited set of stationary phases can separate a wide variety of molecules and maintain good peak shape without mobile-phase additives.
Column Triage
How do you react to symptoms that indicate your liquid chromatography column has major problems?
Headspace Sampling
A clear understanding of the chemical system of the sample in headspace - and how temperature and peak volume affect peak areas, sensitivities, and repeatability - will improve headspace analysis.
Vol 29 No 10 LCGC North America October 2011 Regular Issue PDF
Click the title above to open the LCGC North America October 2011 regular issue, Vol 29 No 10, in an interactive PDF format.