Salting-out Liquid-Liquid Extraction (SALLE)
Ron Majors discusses the technique of Salting-out Liquid-Liquid Extraction (SALLE) and provides some examples of its successful applications.
From the Editor: PharmSep 2009: A Survival Guide to the Modern Separations Lab
At LCGC, our editorial mission revolves around providing practical solutions and nuts and bolts advice to help chromatographers and separation scientists in their labs everyday.
Pinning Down Tailing Peaks, Part II: Quantitative Measurement
John Hinshaw discusses the effects that peak tailing has on quantitative measurement of peak height and area.
A Novel Sample Preparation Approach to Increase the Throughput of Pesticide Analysis by LC–MS-MS
The authors evaluate a new approach to sample preparation for the analysis of pesticides in raw agricultural commodities.
Standardizing Proteomics
Following the sequencing of the human genome, the biological science community has moved to tackle the human proteome.
Analytical Method Validation for Biotechnology Proteins, Peptides, and Antibodies
The authors explore how true (complete) method validation of biopharmaceuticals must be forthcoming.
Calibration Curves, Part V: Curve Weighting
This is the fifth and final installment in a series of columns about various aspects of calibration of LC methods.