Essentials of LC Troubleshooting, Part III: Those Peaks Don’t Look Right
We explain several of the more frequent causes of bad peak shapes in liquid chromatography and provide tips on how to remedy them.
Column Overload in PLOT Columns
Knowing the variables that most affect the sample loading capacity in a porous layer open tubular (PLOT) column is vital to determining how much sample to inject.
The Pharmaceutical Industry and the Separation Scientist: Perspectives, Trends, and Career Opportunities
We kick off a new article series that offers an insider’s view of the pharmaceutical industry, focusing on the role of separation science and separation scientists.
Establishing Analytical and Functional Comparability for Biosimilars
Recent assessments of four biosimilars illustrate how a combination of orthogonal, high-resolution tools is used to demonstrate analytical and functional biosimilarity.
Mentorship in the Time of Covid-19: Finding the Silver Lining
Having to handle mentorship remotely during the pandemic created challenges but also spurred us to think creatively.
Sample Preparation Strategies for Characterizing RNA Modifications in Small-Volume Samples and Single Cells
Advances in sample preparation have enabled analysis of RNA modifications in single cells, paving the way to discovering new insights into the functions of these molecules.
Determination of Organophosphate Esters in Water Samples Using Gas Chromatography–Mass Spectrometry (GC–MS) and Magnetic Solid-Phase Extraction (SPE) Based on Multi-Walled Carbon Nanotubes (MWCNTs)
A GC–MS method, coupled with magnetic SPE with multi-walled carbon-nanotube (MWCNT)-coated iron oxide as the adsorbent, was developed for analyzing organophosphate esters in environmental water samples.
