June 2022

Lipids in SFC are mainly separated according to their lipid classes, which simplifies quantification with standards. In this study, SFC coupled with drift time IM‑QTOF-MS was used to characterize the HepG2 lipidome.

Retention time fluctuations are challenging to deal with, especially in two-dimensional liquid chromatography (2D‑LC) separations. Here, two approaches are presented that can help navigate this challenge.

The basic types of column overload (volume and mass) and the variables that most affect the sample loading capacity in PLOT column chromatography are examined.

An overview of mRNA-based vaccine production and a discussion on the methods that are currently in use to check the quality of these vaccines.

LCGC Europe spoke to Wouter Knol from the University of Amsterdam, The Netherlands, about co‑polymers, the difficulties surrounding their analysis, and what pyrolysis-gas chromatography (Py‑GC) offers in comparison to other techniques when analyzing co-polymers and their sequence.

The 10th International Symposium on Recent Advances in Food Analysis (RAFA 2022) will take place in Prague, Czech Republic, on 6–9 September 2022.