The Column-02-22-2016
Characterizing Biological Processes in Single Cells Using Capillary Electrophoresis
February 22nd 2016The characterization of transcripts, proteins, peptides, and metabolites in cells is important to study disease mechanisms and develop novel therapeutics. Peter Nemes - from the George Washington University, Washington, USA - spoke to The Column about the important role of capillary electrophoresis–electrospray ionization (CE–ESI) and time-of-flight mass spectrometry (TOF-MS) in this area of research.
Extraction and Quantification of Mycotoxins in Peanut Butter Using SFE–SFC–MS
February 22nd 2016Aflatoxins are poisonous and carcinogenic chemicals that occur in nature in soil, hay, and grains. When contaminated food is processed, aflatoxins can enter the general food supply chain and can be dangerous for humans and animals. Time- and cost-efficient analytical methods can ensure food safety. Compared to conventional manual methods the use of “supercritical” CO2 for supercritical fluid extraction (SFE) as well as chromatographic separation (supercritical fluid chromatography [SFC]) of aflatoxins offers a more efficient process while reducing solvent consumption.
Discovering the Drug Habits of Nightclubbers and Criminals Using UHPLC
February 22nd 2016The Norwegian Institute of Public Health conducted a study into the drug use habits of nightclubbers and arrested criminals in Oslo, Norway. The study used UHPLC–MS–MS to analyze the drug-use profiles of nightclubbers and criminals arrested while under the influence of drugs to develop an understanding of drug use patterns in these groups.
Sciex Joins with Children’s Medical Research Institute to Advance Proteomic Profiling
February 22nd 2016Sciex has announced it is teaming up with the Children’s Medical Research Institute to help equip The Australian Cancer Research Foundation International Centre for the Proteome of Cancer facility with tools to advance its large‑scale proteomic profiling studies.
Compositional Analysis of Honeybee Venom for Proteomics
February 22nd 2016Research into honeybee venom is being performed to identify active proteins acting as allergens and toxins. Researchers combined LC–MALDI-TOF/TOF-MS–MS, LC–ESI-QTOF-MS–MS, and a combinatorial peptide ligand library enrichment method to detect 269 proteins.
