Michael J. Telepchak

As a result of the rapid growth of the cannabis industry, many testing laboratories are looking for efficient, reliable, and cost-effective analytical methods to analyze chemical residues, such as pesticides, mycotoxins, solvent residues, terpenes, and heavy metals, as well as cannabinoid concentration in cannabis-infused edibles and beverages. In this article, QuEChERS (quick, easy, cheap, effective, rugged, and safe), a sample preparation technique widely adopted in the food testing industry, is introduced to the discipline of forensic testing as a viable method for the extraction of pesticides and cannabinoids in various complex sample matrices. The claimed amounts of cannabinoids versus the actual amounts are compared, as well as the pesticide residue levels in edible and beverage samples.

Research scientists in the cannabis field are tasked with validating robust methods that can be seamlessly transitioned into production laboratories. Unlike typical disciplines where controls are easily (and legally) obtained through known manufacturers, analytical chemists working for both consumable vendors as well as cannabis laboratories must do their best to develop methods often without such resources at their disposal. As the industry matures and additional regulations are adopted, the evolution of the pesticide testing subsection continues to be vastly different depending on the jurisdiction one does business in. This creates an interesting challenge for commercial scientists tasked with developing methods that will appeal to a majority of their consumers, while also generating unexpected hurdles to said laboratories once the methods are placed into production. Ace Analytical Laboratory, located in Las Vegas, Nevada, has successfully adopted and validated pesticide testing methods for their cannabis laboratories and has gained valuable insight into how to best work with such a difficult matrix. In conjunction with UCT, LLC, an overview of best practices and method development techniques for pesticide testing in cannabis is discussed below and told from a technical perspective.

As a result of the rapidly growing cannabis industry, many testing laboratories are looking for efficient, reliable, and cost-effective analytical methods to analyze chemical residues, such as pesticides, mycotoxins, solvent residues, terpenes, and heavy metals, as well as cannabinoid concentration in cannabis-infused edibles and beverages. In this article, QuEChERS (quick, easy, cheap, effective, rugged and safe), a sample preparation technique widely adopted in the food testing industry, is introduced to the discipline of forensic testing as a viable method for the extraction of pesticides and cannabinoids in various complex sample matrices. Comparison of the claimed amounts of cannabinoids versus the actual amounts as well as the pesticide residue levels in edible and beverage samples is discussed.

A novel, simple, rapid and effective method to determine pesticide residues in red wine samples is described.

A novel, simple, rapid and effective method to determine pesticide residues in red wine samples is descibed.

Sample preparation in this study involved QuEChERS extraction followed by a filter-based cleanup method that is easier and faster than dispersive solid-phase extraction.

Phenazepam is becoming a drug of interest in forensic laboratories. This new procedure will enable forensic toxicologists to analyze phenazepam in biological fluids quickly and easily.

An SPE procedure is described that isolates both psilocybin and psilocin from urine samples for LC–MS-MS analysis.