Super Charged Separations: How Utilizing New Column Chemistries Can Improve the Chromatography of Basic Compounds

Learn how to use positively charged stationary phases combined with superficially porous particle technology to improve the chromatography of basic compounds, including both small molecules and peptides. Improvements in loading capacity and peak capacity will be demonstrated.

Register Free: https://www.chromatographyonline.com/lcgc_w/super-charged

Event Overview:

In LC and LCMS separations, tailed peak shapes with basic compounds at high concentrations is a problem commonly observed when low ionic strength mobile phases are employed, such as those using formic acid. A way to improve the peak shape and sample load capacity is to use a stationary phase containing a positive charge. Application examples demonstrating the impact of positively charged surface (PCS) stationary phases will be presented for both small molecules and peptides. In addition, the webinar will highlight speed and efficiency advantages of using such phases in combination with superficially porous particle columns.

Key Learning Objectives:

• Know when to use positively charged surface phase SPP columns.
• Understand the advantages of positively charged surface phase SPP columns.
• Improve the peak shapes of basic analytes with positively charged SPP columns.

Who Should Attend:

• Method developers
• Lab managers
• Scientists
• Chromatographers
• QA/QC managers

Speaker:

Stephanie Schuster, Ph.D.
Senior Technical Support Scientist
Advanced Materials Technology

Beginning in June of 2009, Dr. Stephanie Schuster joined Advanced Materials Technology, Inc. (AMT) located in Wilmington, DE as a research scientist working with Dr. Jack Kirkland. In this position, Dr. Schuster provided contributions to the commercial development of products specifically designed for the separation of peptides and proteins. During the summer of 2015, Dr. Schuster transitioned from research and development activities to applications development and quality assurance. She is currently a senior technical support scientist at AMT. As such, Dr. Schuster works closely with AMT’s worldwide network of distributors and assists customers with optimizing and trouble-shooting their applications. Her primary interests are separations and novel materials development. Dr. Schuster has several peer-reviewed articles and is currently a member of the Chromatography Forum of the Delaware Valley.

Register Free: https://www.chromatographyonline.com/lcgc_w/super-charged