Application Notes: GC
E-Cigarette and E-Liquid Vapor Analysis for Regulatory Compliance
July 8th 2016In May the EU tobacco products directive became applicable setting out rules governing the manufacture, presentation and sale of tobacco and related products, and the US FDA extended its authority over regulation of tobacco products to include electronic nicotine delivery systems (ENDS) such as e-cigarettes. This Application Note describes a versatile screening method for tackling the challenge of regulatory compliance and quality control in this rapidly expanding industry.
E-Cigarette and E-Liquid Vapour Analysis for Regulatory Compliance
July 8th 2016In May the EU tobacco products directive became applicable setting out rules governing the manufacture, presentation and sale of tobacco and related products, and the US FDA extended its authority over regulation of tobacco products to include electronic nicotine delivery systems (ENDS) such as e-cigarettes. This Application Note describes a versatile screening method for tackling the challenge of regulatory compliance and quality control in this rapidly expanding industry.
Comprehensive Tobacco Smoke Analysis Using GC×GC–TOF MS with Tandem Ionization
June 3rd 2016This Application Note demonstrates the enhanced separation and unparalleled sensitivity that can be achieved in the characterisation of cigarette smoke GC×GC with BenchTOF time-of-flight mass spectrometry, aided by Tandem Ionisation for simultaneous acquisition of hard and soft EI data.
Extraction Method for Pesticides in Poultry Fat
Using a targeted solid phase extraction (SPE) method and GC–ECD analysis, chlorinated pesticides are extracted from poultry fat resulting in a method that decreases the amount of labor and reagents when compared to the USDA-FSIS CHC2 method.
Extraction Method for Pesticides in Poultry Fat
Using a targeted solid phase extraction (SPE) method and GC–ECD analysis, chlorinated pesticides are extracted from poultry fat resulting in a method that decreases the amount of labor and reagents when compared to the USDA-FSIS CHC2 method.
Extraction of Cannabinoids from Brownies
April 7th 2016Cannabinoids are successfully extracted from a complex brownie matrix using the QuEChERS sample preparation technique, significantly reducing the presence of matrix interferences. The resulting clean samples are analyzed by GC–MS using a specialized deactivated GC column to provide heightened peaks for the cannabinoid compounds.
Improved Analysis of EPA Method 625
April 7th 2016EPA Method 625 is greatly simplified by using solid phase extraction (SPE) as an alternative to traditional liquid-liquid extraction (LLE). Using this SPE technique, paired with a sensitive GC–MS analysis, increases throughput and data quality, while decreasing manual labor and solvent usage.
Extraction of Cannabinoids from Brownies
April 7th 2016Cannabinoids are successfully extracted from a complex brownie matrix using the QuEChERS sample preparation technique, significantly reducing the presence of matrix interferences. The resulting clean samples are analyzed by GC–MS using a specialized deactivated GC column to provide heightened peaks for the cannabinoid compounds.
Improved Analysis of EPA Method 625
April 7th 2016EPA Method 625 is greatly simplified by using solid phase extraction (SPE) as an alternative to traditional liquid-liquid extraction (LLE). Using this SPE technique, paired with a sensitive GC–MS analysis, increases throughput and data quality, while decreasing manual labor and solvent usage.
Improvements in your LC–MS-MS Analysis
April 7th 2016Phospholipid removal proves to yield superior results as compared to a traditional protein precipitation step when analyzing a complex plasma matrix via LC–MS-MS. The results displayed a decrease in ion suppression, increased analyte sensitivity, and an improvement in column lifetime.
Improvements in your LC–MS-MS Analysis
April 7th 2016Phospholipid removal proves to yield superior results as compared to a traditional protein precipitation step when analyzing a complex plasma matrix via LC–MS-MS. The results displayed a decrease in ion suppression, increased analyte sensitivity, and an improvement in column lifetime.
Drug Analysis from Oral Fluids
April 7th 2016Using oral fluid as the matrix, a viable and simple solid phase extraction method for a wide range of drugs is developed. Several oral fluid collection devices were evaluated to determine the effectiveness of the cleanup procedure, ultimately confirming that the method is both robust and widely applicable.