Application Notes: GC-MS
Analysis of Impurities in APIs
Mesylate and besylate are potentially genotoxic impurities in pharmaceuticals. This app note introduces analysis of sulfonic acid esters utilizing Shimadzu's GCMS-QP.
Comparison of soft drinks with GCxGC
Untargeted comparison of flavour profiles of popular brand soft drinks using immersive sorptive extraction, GCxGC–TOF-MS and chemometrics.
Quantitation of 5 NSAs in Metformin APIs
USP General Chapter <1469> ensures appropriate control of NSAs in drug products. This application replicates NSA determination in APIs using Shimadzu's GCMS-TQ8050 NX.
PFAS screening during application of foam
Application note shows how thermal desorption GC–MS is used to monitor the release of PFAS during the application of aqueous film-forming foam (AFFF).
Monitoring environmentally damaging gases in PFAS removal
Demonstrating how commercially available TD equipment is used to monitor CF4 & other products of incomplete destruction (PIDs) resulting from PFAS removal technologies.
Measurement of PFAS in indoor air (Nov 2023)
This study investigates the performance of a high-throughput automated thermal desorption instrument coupled to GC–MS/MS for PFAS analysis.
Cannabis Potency Analysis by GC-MS
This application note utilises SCION's GC-MS to test for cannabinoids, providing method conditions and sample preparation techniques to validate methods.
Measuring PFAS pollution in ambient air (Nov 2023)
Measuring PFAS pollution in ambient air with TD–GC–MS/MS at concentrations low as 2 pg/m3. Each of 19 targeted compounds had linear calibration with high repeatability.
Cannabis Terpene Testing Using GC SQ-MS
This application note provides insights into how to monitor the different cannabis strains, and showcases how the Horwitz ration can be a useful tool in this analysis.
Headspace GC-MS Analysis of Cannabis Residuals
Discover how Headspace GC-MS is used to test cannabis samples for residual solvents and pesticides in this application note.
Plant volatiles: Comparing sampling techniques
Passive sampling of plant volatiles using TF-SPME and GERSTEL Twister, respectively, is compared with active sampling onto PDMS foam- and TenaxTA-filled Tubes
Off-Odors by Sensory Directed GC–MS
Lipid oxidation generates off-odors in food, edible oils, and fats. DHS or Thermal Extraction-GC–MS/O using Sensory Directed Analysis quickly identifies off-odors
PCA and Sensory Honey Aroma Differentiation
An analytical approach combined with PCA is compared to sensory-directed analysis (SDA) for differentiating honey from multi-floral, wildflower, and clover sources
Smoothie flavor analysis by SA-SBSE-GC–MS
Determination of flavors in smoothies using standard- and solvent-swollen Twister® stir bars, liquid desorption, and LVI-GC/MS for enhanced recovery of polar compounds
Smart-Ramped Pyrolysis-GC–MS for Forensic Analysis (Oct 2023)
Smart Ramped Pyrolysis-GC–MS analysis of forensic samples such as paint, adhesive tape, and mascara gives maximum information in a single run without method development
Microplastics Analysis Using Micro-Furnace Pyrolyzer
This application note demonstrates how splitless micro-furnace pyrolysis increases the sensitivity of microplastic measurements.
Air quality: PAMS analysis
Air quality measurement: Continuous, cryogen-free on-line monitoring of PAMS in ambient air using hydrogen carrier gas using EPA PAMS method.
Monitoring chemical warfare agents (Sept 2023)
Tube-based thermal desorption for monitoring chemical warfare agents Malathion, Russian VX and mustard gas at ultratrace levels without degradation or losses.
GC-MS for US EPA Method TO-15A
This app note describes automated, high-performance GC–MS analysis of humid 'air toxics' samples in canisters, using a cryogen-free system for preconcentration and TD.
Optimised hydrogen fuel impurity analysis
This application note shows the robust, reproducible analysis of trace VOCs in hydrogen fuel by TD–GC–MS/SCD.
Analysing microplastics in salt samples (Sept 2023)
Using thermal desorption–GC–MS is to address multiple challenges in the detection of microplastics in different salt samples.
Measurement of PFAS in indoor air
Analysis of VOCs using hydrogen carrier gas
TD–GC–MS analysis of VOCs in air using H2 carrier gas meets all the performance criteria cited in US EPA Method TO-17, including linearity, reproducibility & MDLs.
VOC Monitoring in the ppqV Range
Ambient air analysis and study of the new IONICON Fusion PTR-TOF, providing ultrahigh sensitivities up to 80 000 cps/ppbV, high mass resolving power and ppqV detection limit
Chocolate real-time aroma analysis with PTR-TOF
Complex food & flavor headspace analysis with the new FUSION PTR-TOF 10k demonstrates benefits of high mass resolving power & extreme sensitivity for fast measurements.
Food Safety Testing
Automated, high-sensitivity analysis of residual fumigants for food safety testing by multi-step enrichment–headspace–trap (MSE–HS–trap) with GC–MS.
Purge and Trap EPC-Controlled Calibration Curves
The CDS 8500 Purge and Trap electronic pressure control (EPC) is used for automated preparation of calibration curves.
Purge and Trap Automated Sample Dilution
The CDS 8500 Purge and Trap system is used to perform automated sample dilution to prepare calibration curves.
Increase Sensitivity with Pyroprobe Sample-Stacking
This application note introduces a sample-stacking technique to improve sensitivity for low concentration polymer samples.
UV Study of Polypropylene
A rapid, automated polymer degradation study of polymers containing UV stabilizers under ultraviolet (UV) light in a temperature-controlled environment.