Application Notes: GC-MS
Optimizing Column Lifetime of TSK-GEL Size Exclusion Columns
December 2nd 2006Column lifetime is a more and more important issue when developing an analytical method for HPLC. Besides sample treatment, column cleaning and storage, operational parameters of the analytical method will have an influence on column lifetime. This question may not always be addressed early enough in the methods development process.
Analysis of Polybrominated Diphenyl Ethers Using the Clarus 500 GC–MS
July 2nd 2006This application note will demonstrate a GC–MS analysis of common polybrominated diphenyl ether (PBDE) congeners. An optimized method will allow the Clarus GC–MS to provide ample separation and high yields of all PBDE congeners. The extended mass range of the Clarus 500 MS and high-mass calibration will produce mass spectra with very high levels of accuracy.
Trace Analysis of Brominated Flame Retardants with High Resolution GC–MS
July 2nd 2006Polybrominated diphenyl ethers (PBDEs) are among the most important and widely used flame retardants. Recent legislation banned certain PBDE congeners.? EU directive 2003/11/EC prohibits the use of Penta-BDE and Octa-BDE for the member states of the European community.? Therefore, analysis of PBDEs have received increased interest as a result of their known toxicity.
Tandem GC–MS Analysis of Pesticides in Food Oils by Large Volume Injection with a Back-flush Option
September 2nd 2005As the global sourcing of foodstuffs becomes more common, the number of pesticide analyses performed continues to increase to test these sources for compliance with various regulations. The sheer number of analyses dictates that utilized methods must be reliable, robust and inexpensive.
Determination of Protease Inhibitors Used in the Treatment of HIV
March 2nd 2005Protease inhibitors are a class of anti-HIV drugs used in combination therapy to block replication of the HIV virus in a person's blood. It is important to monitor the levels of these drugs in the patient since resistance can develop at low levels and at high levels the drug can exhibit toxic effects.