Retention of polar compounds and the separation of closely related compounds have become two very challenging areas for chromatographers today. Often the solution seems to lie beyond the reach of traditional silica-based stationary phases. In this "Column Watch" installment, guest author Paul Ross reviews the role of graphite carbon as a means of solving these problem separations.
LCGC 18(1), 14–27 (2000).Common Challenges in Nitrosamine Analysis: An LCGC International Peer Exchange
April 15th 2025A recent roundtable discussion featuring Aloka Srinivasan of Raaha, Mayank Bhanti of the United States Pharmacopeia (USP), and Amber Burch of Purisys discussed the challenges surrounding nitrosamine analysis in pharmaceuticals.
Extracting Estrogenic Hormones Using Rotating Disk and Modified Clays
April 14th 2025University of Caldas and University of Chile researchers extracted estrogenic hormones from wastewater samples using rotating disk sorption extraction. After extraction, the concentrated analytes were measured using liquid chromatography coupled with photodiode array detection (HPLC-PDA).