Retention of polar compounds and the separation of closely related compounds have become two very challenging areas for chromatographers today. Often the solution seems to lie beyond the reach of traditional silica-based stationary phases. In this "Column Watch" installment, guest author Paul Ross reviews the role of graphite carbon as a means of solving these problem separations.
LCGC 18(1), 14–27 (2000).Detailed Glycosylation Analysis of Therapeutic Enzymes Utilizing Comprehensive 2D-LC–MS
January 3rd 2025In this article, the use of comprehensive two-dimensional liquid chromatography (LC×LC) coupled to mass spectrometry (MS) for characterizing glycosylation of therapeutic enzymes is presented.
Trending on LCGC: The Top Content of 2024
December 30th 2024In 2024, we launched a content series, covered major conferences, presented prestigious awards, and continued our monthly Analytically Speaking podcasts. Below, you'll find a selection of the most popular content from LCGC International over the past year.