LCGC North America
It seems hard to believe that we are already nearing the holidays and the end of 2009. And for many in the world of separation science, after weathering difficult economic conditions, solvent shortages, and more, welcoming in 2010 will be something to look forward to indeed.
It seems hard to believe that we are already nearing the holidays and the end of 2009. And for many in the world of separation science, after weathering difficult economic conditions, solvent shortages, and more, welcoming in 2010 will be something to look forward to indeed. However, the end of the year can also provide us with a unique perspective and a chance to take stock of the marketplace, and at LCGC, we have done just that.
David Walsh
This month, LCGC presents the results of our most recent HPLC User Survey in Ron Majors' November installment of "Column Watch." In such an eventful year, the results of this survey are more informative — and intriguing — than ever before. For now, we finally have hard data to answer many lingering questions that to this point have been answered largely by consulting popular wisdom and word-of-mouth. Have changes in thinking toward solvent usage changed the overall HPLC market? Which techniques have taken off under these market conditions and which have seen decreases, and most importantly, why? Which column types are being used more than ever, and which types have fallen in popularity? Ron's column answers these questions and more, giving readers their clearest picture yet of where the market stands after the rollercoaster of a year that was 2009.
As always, LCGC strives to bring you the nuts-and-bolts information from the front lines of the separations laboratory, and the 2009 HPLC User Survey is just another example of this commitment. The results presented in this survey come not from revenue projections or informal discussions, rather, they come from having direct interaction with the users performing chromatographic research every day, and we believe this makes them all the more relevant and reliable.
We hope you find this survey and the rest of the industry-leading columns and technical articles in this issue useful, and as usual, feel free to contact us with any comments you may have.
Enjoy the issue.
New Study Uses MSPE with GC–MS to Analyze PFCAs in Water
January 20th 2025Scientists from the China University of Sciences combined magnetic solid-phase extraction (MSPE) with gas chromatography–mass spectrometry (GC–MS) to analyze perfluoro carboxylic acids (PFCAs) in different water environments.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ion used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
A Guide To Finding the Ideal Syringe and Needle
January 20th 2025Hamilton has produced a series of reference guides to assist science professionals in finding the best-suited products and configurations for their applications. The Syringe and Needle Reference Guide provides detailed information on Hamilton Company’s full portfolio of syringes and needles. Everything from cleaning and preventative maintenance to individual part numbers are available for review. It also includes selection charts to help you choose between syringe terminations like cemented needles and luer tips.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Oasis or Sand Dune? Isolation of Psychedelic Compounds
January 20th 2025Magic mushrooms, once taboo, have recently experienced a renaissance. This new awakening is partially due to new findings that indicate the effects of psilocybin, and its dephosphorylated cousin psilocin may produce long lasting results for patients who might be struggling with anxiety, depression, alcohol and drug abuse, and post-traumatic stress disorder. Hamilton Company has developed a methodology for the isolation and identification of 5 common psychedelic compounds used in the potential treatment of disease. The PRP-1 HPLC column resin remains stable in the harsh alkaline conditions ideal for better separations.