The Chromatographic Society and the Royal Society of Chemistry Analytical Division North East Region has organized a meeting to be held on 22 November 2018 in the Stadium of Light, Sunderland, UK.
Photo Credit: The Chromatographic Society
The Chromatographic Society and the Royal Society of Chemistry Analytical Division North East Region has organized a meeting to be held on 22 November 2018 in the Stadium of Light, Sunderland, UK.
The organizers are planning to make the conference a little different than usual. The meeting will not be introducing new chromatographic innovations to pharmaceutical researchers. Instead, the conference will reflect on the enduring strength of pharmaceutical development and manufacture in the UK. The unmet analytical challenges facing these areas of the industry will be explored and emerging technologies reviewed to assess those that potentially offer the best solutions for the immediate future. Ahead of the meeting analytical scientists supporting pharmaceutical development and manufacture will be invited to comment on the most important unmet analytical needs they are facing, with a view to speakers and vendors responding at the meeting. For more information, please visit: http://chromsoc.com/event/seperation-science-driving-pharmaceutical-development-and-manufacture
For initial enquiries please contact:
Scientific programme: john.lough@sunderland.ac.uk
Exhibition opportunities: heather.linnell@agilent.com
Local arrangements: roger.reeve@sunderland.ac.uk
Determining Neurotransmitters in Spinal Cords with UHPLC
February 18th 2025Researchers at Jilin University (Changchun, China) developed a highly sensitive, rapid, and accurate method for analyzing neurotransmitters (NTs) in rat spinal cord tissue. Ultra-high performance liquid chromatography-triple quadrupole tandem mass spectrometry (UHPLC-QqQ-MS/MS) in conjunction with ultra-ionic liquid dispersive liquid-liquid microextraction (UA-MIL-DLLME) were used to extract NTs for analysis.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
Revolutionizing LC-MS with Next-Gen Separation for Cyclic Peptide Analysis
February 17th 2025Cyclic peptides, known for their stability and high specificity, are promising therapeutic agents in the fight against cancer, infections, and autoimmune diseases. However, developing effective cyclic peptides presents numerous challenges, including poor pharmacokinetics, efficacy, and toxicity. Traditional methods like liquid chromatography tandem-mass spectrometry (LC-MS/MS) often struggle with resolving isomeric linear peptide metabolites, posing significant risks in safety, efficacy, and regulatory approval. In this paper, Komal Kedia, PhD, will share how she leveraged MOBIE’s high-resolution ion mobility-mass spectrometry (IM-MS) system to achieve a 72% reduction in run times, 200% greater resolving power, and enhanced accuracy in identifying “soft spots” prone to enzymatic degradation.