Reducing Sample Size and Obtaining Representative Samples

A new study, published by a researcher from Chemical Characterization Solutions in Minnesota, explored a new approach for sample preparation for the chemical characterization of medical devices.

Karolinska University Hospital researchers recently tested new approaches for analyzing drugs of abuse in oral fluids.

An automated solid-phase extraction (SPE) method has been developed to detect cyanotoxins in water.

Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.

This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.

Hydrophobic deep eutectic solvents have proven useful in extracting non-polar target compounds, though researchers have shown there is room for further development.